Gerald Forster for Newsweek
Rosenthal: Forty years working with addicts
VIEWPOINT

Sadly, There is No Magic Bullet

Addiction is not solely a disease of the brain. The case for holistic treatment.

 
 
 

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Drugs—we love them. We've come to believe in a prescription for every condition and a pill for every ill. Industry advertising tells us what doctors should prescribe for a catalog of ailments, real or imaginary. And this pharmacological boom has proven particularly creative and bountiful in the treatment of addiction.

Advances in brain science have given us a new understanding of addiction and its neurological basis. They have made possible a spectrum of anti-drug drugs. The latest of these, now in development, are vaccines that may be able not just to treat addiction but to prevent it as well. These vaccines would train the immune system to recognize psychoactive substances that now slip unidentified into the bloodstream (cocaine, for example) but, when identified, can be destroyed before they can reach the brain.

It sounds great. And the new medications will have their place as treatment protocols evolve. In our passion for the prescription quick fix and pharmacological solution, however, we should recognize that drugs alone are not the answer to addiction.

The law of unintended consequences warns us that there's a downside to just about every advance. So discovering that addiction involves profound changes in the brain has led to a widespread assumption that addicts are powerless over their condition—that drugs have hijacked their brains. This, in essence, rules out free will and the possibility that some addictive behavior may be voluntary. It is a seductive proposition, for it suggests that the addict is incapable of self-control, and hence cannot be responsible for his or her behavior.

It is clearly true that addicts become increasingly incapable of controlling their behavior, for the compulsive nature of their drug use is the defining characteristic of their addiction. Moreover, addiction is far from an equal opportunity affliction. Certain individuals—by heredity, mental illness or age—are far more vulnerable than others. There appears to be a genetic component to addiction, and a substantial proportion of addicts suffer from co-occurring mental illness. As parents and policymakers, the vulnerability of teens rightly concerns us most, for the adolescent brain is a work in progress. While the brain's pleasure- and sensation-seeking center is up and running strong at puberty, that portion of the brain exercising control over impulsive and irrational behavior isn't yet fully hooked into the mental communication system until the mid-20s. Lives can be destroyed before they even begin.

My work—I founded Phoenix House, the drug and alcohol treatment program, 40 years ago—and the work of my colleagues would be much easier if the brain were the sole culprit in addiction. As jarring as it can be to say this in a milieu constantly shaped by reports of new scientific insights, it must be said: biology is not necessarily destiny. To accept the proposition of an addict's powerlessness is to eliminate volition from the equation, for we know from hard evidence that addicts can and do kick the habit. And, no matter how difficult it eventually becomes to exercise choice, there is always a period at the outset when choice is not only possible but relatively easy.

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  • Posted By: muskan @ 02/11/2009 4:36:15 PM

    Western Massachusetts is a loosely defined geographical region of the U.S. state of Massachusetts which contains the Berkshires and the Pioneer Valley. Most commonly, the region is considered to include Berkshire, Franklin, Hampshire, and Hampden counties.
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    muskan


    Alcoholism Information-Alcoholism Information

  • Posted By: muskan @ 02/11/2009 4:33:42 PM

    Western Massachusetts is a loosely defined geographical region of the U.S. state of Massachusetts which contains the Berkshires and the Pioneer Valley. Most commonly, the region is considered to include Berkshire, Franklin, Hampshire, and Hampden counties.
    -------------
    muskan


    <a href="http://www.alcoholisminformation.org">Alcoholism Information</a>-Alcoholism Information

  • Posted By: Alcoholism @ 09/21/2008 10:20:20 AM

    That there is "no magic bullet" comes from an ideology with vested interests - both commercial and religious - that there will never be a "cure for alcoholism." The implications are that while we may even find a cure for cancer, a far more complex physiological illness - we will never find one for drug and alcohol addiction. Yet 40 years of research at the National Public Health Institute in Helsinki, Finland proves that there is a cure - close to a magic bullet. The Cure for Alcoholism as discovered by David Sinclair and team of addiction researchers is known as "pharmacological extinction" which requires that patients take an opioid or opiate antagonist medication such as nalmefene or naltrexone BEFORE drinking alcohol. Within 3 months the craving and drinking diminish so that patients once again are able to control their drinking - or for the first time choose to abstain. Pharmacological extinction became known as The Sinclair Method. Backed by over 70 clinical trials - many of them double-blind placebo controlled - the treatment comes as close to a magic bullet for alcoholism through the formula Naltrexone + Drinking = Cure (Naltrexone has no effect if taken with instructions to abstain). A new book by Drs. Roy Eskapa and David Sinclair is called "The Cure for Alcoholism" - it explains the science behind addiction in the brain and how physiological addiction can literally be removed from the brain and nervous system - about 90% of the battle - instead of arduous abstinence based rehab and detox often at great cost and with almost certain relapse rates of 90% withing a few months of completing treatment. The Cure for Alcoholism presents the origins of Sinclair's breakthrough discoveries, offers readers a 5 Step plan toward cure, case studies, a summary of 70 clinical trials, the reasons why this treatment has not yet been widely disemanated in the US, and a chapter for prescribing physicians.

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