OBESITY

The Pleasure Factor

Using milkshakes and brain scans, researchers find that some women are genetically predisposed to get less enjoyment from eating and may overeat to compensate.

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  • Posted By: Doc HowI @ 11/23/2008 12:04:09 PM

    If I ever saw rationalization of overeating before Sarah Kliff takes the cake (is that a pun?). One thing we can say with certainty is that there are kook studies all over the place, and to excuse your overeating and weakness by quoting a study that says you can't help it, you are genetically predisposed, is the the worst kind of rationalizing ever. Just put the frickin twinkie down Sarah and blame the person responsible, yourself.

  • Posted By: Josephsco @ 10/21/2008 8:08:16 AM

    Actually Serotonin is more commonly a target of anti-depressants although there are drugs that target other neurotransmitters including dopamine for treating depression. And yes Depression and obesity are linked as are obesity and many other mental illnesses mostly in that obesity or the opposite anorexia can be a sympthom of these illnesses. I think its exciting that doctors are finally realizing that obesity is a illness that has biological factors beyond the persons control not just a illness of choice and over indulgence. I wouldnt hold your breath though while you wait for them to actually accept this research and provide treatments. Doctors seem to be universally opposed to treating obesity as anything other than a personalty trait that needs changing and lecturing their patients many times to the exclusion of treatment of other illnesses the person comes in for treatment for.

    • Posted By: miskaffon @ 11/02/2008 10:43:52 AM

      Exectly; all you have to do are read comments on any article on any news source regarding anything to do with weight and there will literally be hundreds of people talking about the "worst" people in this country. No group of people is more hated in this country; there is more tolerance toward mass murderers than there is a person who is overweight!!! Doctors are the worst at this; I feel that in many cases doctors and "helpers" who berate and refuse to do anything but openly criticize an overweight person contribute greatly to the feelings of hopelessness and continued deterioration of health that result. I have been refused treatment by an "obesity doctor" because I deviated once from his crackpot "treatment" and had a teaspoon of ketchup on the HORRIBLE 100% beef mixture he had me choking on....disgusting! Instead, people in this country say you must go it all on your own, not to seek treatment because we shouldn't expect help with our personality "failure".

  • Posted By: Arwen8Aragorn @ 10/22/2008 5:11:59 PM

    Just as an FYI, I do NOT eat junk food every day. I hadn't had a Twinkie in over 20 YEARS when I discovered they were disgusting and I have had no more than ONE milkshake in the past year. It has nothing to do with "continually eating junk food".

  • Posted By: Arwen8Aragorn @ 10/22/2008 5:04:59 PM

    As an overweight person, I think this has a lot of merit. I often eat things expecting a certain taste, texture and pleasure and I usually decide after I've eaten said item that it didn't taste/feel like what I expected. I have started to take down lists of items that sound delicious but just aren't anymore. My number one offender... Twinkies. YUCK! I see them and I remember their creamy, yummy goodness... unfortunately, they are cardboard-tasting pus-filled disgusting things that I continually remind myself do NOT taste good anymore (if they ever did).

  • Posted By: burnor @ 10/22/2008 10:17:36 AM

    What is not really indicated by this article is the debate good old chicken before the egg debate... meaning does low dopaminergic receptor activity cause obesity, or as with many drug addictions does over stimulation of dopamine mediated receptors lead to less response in those areas. This article does a terrible job of parsing out this ambiguity and does readers a bit of a disservice.

  • Posted By: zeth006 @ 10/22/2008 8:35:26 AM

    Porceline, I'm not surprised at all! My parents raised me under a VERY Spartan diet. As a young child, I rarely ever ate out. I remember the days when I would hope upon hope that my dad would announce we were going to eat out at a restaurant or at a food court! At the dinner table, I would long to see some beef or chicken. My face would fall each time I saw numerous vegetable side dishes laid out alongside the occasional dish of fish.

    Now at the age of 22, I have no problems eating a traditional Asian dish that???s composed mainly of tofu, vegetables, and maybe a touch of beef! Unlike most of my friends in American, I???m not a big fan of steakhouses, and I enjoy balancing out my breakfasts with some fruit here and there. It???s almost as though my parents trained my brain from day 1 to not crave beef or fatty foods too much.

  • Posted By: Porceline @ 10/22/2008 7:21:27 AM

    did anyone notice that the studies show that overweight people expect to get more pleasure out of the food than they actually do. it reminds me of the conditioning studies done on pidgeons where when the pidgeons didn't get the seed that they expected they became frustrated and pecked at the button repeatedly. Am I the only one who sees a possible connection? Maybe obease people as well as drug addicts take a hit and get frustrated that they don't get the high they expect and therefore take another and another. Maybe the way to counter obeasity is to retrain the brain not to expect that the food will taste that good. I notice that people who like bland tasting food are rarely overweight and those who like flavourful food typically are obease. It really does sound like a case of conditioning.

  • Posted By: Susan_Wreyford @ 10/21/2008 11:13:12 PM

    Well there is the genetic factor, for instance a long time friend of mine who all her life has been rather large, just as her mother. Though they are on the heavy side they are perfectly healthy. Then there is another long time friend who as a child and adolescent was rather thin, but now is overweight, and her children are overweight. They eat tons of fast food and junk food wondering why they are the way they are. As far as child obesity is concerned, you have to look at today???s forms of recreation. When I was growing up it was playing outside and ridding our bicycles. Today it???s playing games, getting on the computer, and watching television. With the amount of homework they have that doesn???t leave much room for active play. I believe the biggest problem today is ignorance.

  • Posted By: Susan_Wreyford @ 10/21/2008 11:12:46 PM

    Well there is the genetic factor, for instance a long time friend of mine who all her life has been rather large, just as her mother. Though they are on the heavy side they are perfectly healthy. Then there is another long time friend who as a child and adolescent was rather thin, but now is overweight, and her children are overweight. They eat tons of fast food and junk food wondering why they are the way they are. As far as child obesity is concerned, you have to look at today???s forms of recreation. When I was growing up it was playing outside and ridding our bicycles. Today it???s playing games, getting on the computer, and watching television. With the amount of homework they have that doesn???t leave much room for active play. I believe the biggest problem today is ignorance.

  • Posted By: tigerclaw8201 @ 10/21/2008 12:02:41 PM

    I agree with Josephsco. True, perhaps some people can help being obese, but a lot of people can not. I am 26, and I am obese. Mostly due to the fact that I have a disorder that makes me insulin resistant. Between the disorder, and the quality of food that is available in today's fast paced lifestyle, it is very difficult to lose and/or keep the weight off. I dont care what people say, all people are NOT meant to be skinny. Genetics still has a major role to play in it. No one in my family is small, yet we don't eat anymore than our skinny friends. In my personal opinion, playing with genetics is nothing but a time bomb. It may seem like a good idea, but possibly will not in the end. If everyone was meant to be a like, we would be made that way. No one can play God.

    • Posted By: gibsonjamesi @ 10/21/2008 10:20:05 PM

      You can't blame your obesity on insulin resistance. The simple fact is, you DO eat more than your skinny friends, or you are ALOT less active. Calories in vs calories out determines weight gain. It is definitely more difficult for some people to stay motivated and stick to a proper diet/eating schedule, but that may have more to do with food addiction or some other eating disorder. IF your skinny friends lived your exact life style and ate what you ate, they'd be obese too--unless they are much bigger/taller than you, then of course you might be right. are you 5 feet tall and your skinny friendds are 6 feet tall? you need to factor that in.

  • Posted By: crazydgldy @ 10/21/2008 9:25:37 PM

    I've always said my problems with chocolate and sweets were similar to addiction. This really makes sense to me.

    • Posted By: karthy @ 10/21/2008 10:12:50 PM

      Let's compare..In Africa, where there was/is the AIDS pandemic and we are trying to curb the spread; we can not tell the widows who have no other means of feeding their children, other than prostitution, to "stop having sex" while giving them nothing to replace their income...they would understand hte reasoning but would not listen. So we began funded education programs and helped them build income generating projects to provide sustainable means of feeding and caring for their children. In the U.S. where we have such a serious epidemic of obesity, we come up with pills, exercise programs and the like, expecting people to take the initiative to make the change themselves. Other than programs like Weight Watchers, where are the humanitarians who "go to" the source (obese people) and directly offer to step in to educate & help? The 2 epidemics are similar in the sense that just as the women who prostitute themselves for the sake of their children are living in despair and see no hope of a future until someone comes to them, working hand in hand with them until they learn to utilize the tools and lessons which give them hope and then be able to act on it...so is the obese. Why do we feel that Americans do not also deserve our humanitarian care? Neither these women in Africa nor the obese in America are weak, they just lack tools to help them overcome the problem and sustain their goals. I challenge the healthy out there...What are you willing to do to make America a better, healthier place? What are you willing to do the next time you meet an obese person? Are you willing to offer to go to the gym with them, take a walk with them? Talk with them or, talk about them? Keep in mind that both diseases if not treated can produce orphaned children who, without education and treatment will also propagate the illness. Just some thoughts...

  • Posted By: Amelia307 @ 10/21/2008 9:11:40 PM

    Animals produced for human consumption are often given growth hormone stimulants that make them grow faster and fatter to get the meat to market faster. Have any of these research doctors looked into the affects these growth hormones have on humans as a result of eating the meat? I???m not a vegetarian!

  • Posted By: Amelia307 @ 10/21/2008 9:10:02 PM

    Animals produced for human consumption are often given growth hormone stimulants that make them grow faster and fatter to get the meat to market faster. Have any of these research doctors looked into the affects these growth hormones have on humans as a result of eating the meat? I???m not a vegetarian!

  • Posted By: gtfitnow @ 10/21/2008 6:44:20 PM

    Disregard word after the period.

    • Posted By: karthy @ 10/21/2008 8:40:21 PM

      PLease look it at from our point of view. Trainers tell you if you've entered menopause, it's genetic and depression is involved (leading to lack of energy and motivation).....it may not be physiologically possible for you to lose the weight that's accumulated. Then you add the mass of mass media stuff that all promise results so they can get rich... Then you listen to all the supposed studies and theoretical intellectual bantering on what should be but no one true answers to...one removes themselves from living life into the resolve of loneliness and surrender.

  • Posted By: goldi4674 @ 10/21/2008 2:21:35 PM

    I agree with Lindsay; the more you have exposure to something the more you get used to it. I LOVE ice cream but if I had it every day it would get boring. It's something I really look forward to because I don't have it very much. As a competetive runner I can say that we don't pop Advil all the time because if we did it would take a lot more to get the same affect! Put decent food into your body and I promise that a milkshake will evoke all the dopamine you need!

    • Posted By: gtfitnow @ 10/21/2008 6:47:50 PM

      I totally agree with you.

  • Posted By: gtfitnow @ 10/21/2008 6:40:13 PM

    In simple terms, this like a couch potato vs a physically trained person, the first will only be able to take a bit of exercise , while the second could carry on way more. I believe that obese people have trained themselves to overeat, sadly society is always looking for an excuse, and pharmaceutical companies always for a way to make more money, even if that implies giving people false hopes. As a fitness trainer I've trained morbidly obese people who are always looking for a reason to their obesity, other than their eating habits, even thogh is clear as daylight. peopleth

  • Posted By: fixtedwingonwheels @ 10/21/2008 6:29:32 PM

    As we shape ourselfs around our inventions,this could be evolution,just compare our lifestyles to our ancestors...

  • Posted By: islandMD @ 10/21/2008 5:12:23 PM

    typo i meant their - line three

  • Posted By: islandMD @ 10/21/2008 5:06:33 PM

    is this really a genetic predisposition? or could it be genetic enhancement or cultivation of a pattern of behavior that shapes brain physiology and neurotransmitter levels? think about it. we stuff our children with high fat, high calorie meals from a very very young age while they're brains are making critical developmental leaps (through late teens). undoubtedly this is having a significant impact on the findings of this study. i find it troublesome that pharmaceutical companies/media continue to promote this way of conceptualizing the 'problem' -- it clearly benefits big pharma because, according them, the treatment is almost always medication. this also furthers the 'victim' mentality; that we are victims of our genetic makeup which is rarely the case. we have to hold ourselves more accountable for our lifestyle and behavior related to individual/family food preferences and eating patterns. in doing so, we will see dramatic changes in population body compostion. we can no longer rely soley on the 'scientific community' to provide answers to rather common sense problems. there are explicit and implicit motives for the people who perform these studies to continue viewing it from the 'genetic-pharmacologic' pradigm -- it creates lucrative and sustainable business. circular reasoning at its best. taking personal responsibility for our/our families lifestyle is a more efficient and effective and healthy way of addressing the major problem of obesity.

  • Posted By: krwhite83 @ 10/21/2008 4:09:25 PM

    I believe there is a confound here that is being ignored. I do not think that we can claim that lower release of neurotransmitters to pleasurable food is the CAUSE of obesity or overeating. I would argue, rather, that it is the result of overeating. For instance, those who are leaner more than likely do not have chocolate milkshakes very often, and thus drinking one would constitute a treat. However, someone who is very overweight or obese might have sweets on a regular basis, and so drinking a milkshake would be no big deal and therefore less pleasurable. People who abuse cocaine or heroine deplete their stores of dopamine and serotonin, and thus less and less of these neurotransmitters are released when they take their drug of choice. But no one would argue that this lower level of release is the CAUSE of their addiction. It is simply a classic example of tolerance, which results for their substance abuse. Based upon this evidence, I would argue that the lower activity in the fMRI scans for overweight people is a result of their overindulgence, rather than the cause of their obesity.

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