Worse Than SARS?

 

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By contrast, the cure rate of normal TB is . . . ?
Raviglione: . . . . 95 percent. It's very curable. You use a cocktail of four drugs for two months, then two of these drugs for another four months. But in some places, doctors will use only one drug, contrary to the standard protocol. That single drug might kill 99.99 percent of TB bacilli [germs] in your body. You will feel better, because you have dramatically decreased the bacilli—but the one bacillus that survives keeps replicating, because it is not susceptible to the drug treatment. Two months later, the person starts deteriorating again, as the surviving bacillus creates a new, drug-resistant population.

So MDR and XDR are caused by poor treatment of the disease?
Cataldi: Also by misdiagnosis and the unwitting use of counterfeit drugs, so that patients are not treated effectively.

How do you treat XDR?
Raviglione: The two strongest drugs [for normal TB] are ineffective against XDR. The remaining two drugs may still work, but these are weak drugs. So you have to turn to the second-line drugs that are used for MDR. Again, the best of these are ineffective against XDR, so you're left with three or four drugs that are not only weak, but also cause toxic side effects.

What kind of side effects?
Raviglione: Gastrointestinal distress—including diarrhea and stomach aches—liver damage and neurological problems such as psychotic reactions and seizures.

Cataldi: I'm not a doctor, but when I spend time with health workers giving these medications to patients, people will say the medicines make them feel worse. They have a tendency to stop the treatment for this reason.

How expensive is XDR to treat?
Raviglione: The drugs used to treat normal TB are very cheap—$20 for six months of treatment in the developing world. The main cost is medical assistance and oversight to make sure that people take their drugs regularly. By contrast, the drugs used to treat MDR can cost up to $20,000 for the two years of treatment that are required.

I ' ve heard scientists argue that highly virulent diseases like Ebola tend to die out because they kill off their hosts before people can spread them around. Is this true of XDR?
Cataldi: No. You can still infect a lot of people in the months you survive. TB is airborne. It's not like HIV, where you need person-to-person contact. With TB, a carrier can just cough or sneeze—even speak—and spread the disease.

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  • Posted By: Donald C @ 11/04/2008 11:57:58 PM

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  • Posted By: ObamaYesWeCan @ 11/01/2008 5:29:10 PM

    This moronic scumbag Samuel J. Wurzelbacher "Joe the Plumber" had his AZ driver license suspended

    http://www.eastvalleytribune.com/story/128323

    Wurzelbacher, who lived in Mesa in 2000 and had an Arizona driver's license, had his driver's license suspended by the Arizona Department of Transportation Motor Vehicle Division on May 4, 2000, following a nonpayment of a court-imposed fine for civil traffic violations, according to court records.

    ...owes nearly $1,200 in back taxes, according to public records, still owes more than $700 to the Mesa court system.

    Records show he was cited for failure to stop at a red light and for failure to provide proof of insurance on Feb. 9, 2000, in a black Dodge truck at the intersection of Dobson and Baseline roads in Mesa.

    After failing to pay his original fine of $627.50 issued in March 2000, his license was suspended and the fine was handed over to a collection agency along with a 16 percent surcharge. The now-resident of Holland, Ohio, still owes $727.90 to the Mesa Municipal Court, according to court records.


    Hopefully the collection agency will break both of his legs so he'll never be able to walk nor work ever again. This typical Republican scumbag deserves it.

  • Posted By: C. MacLean @ 10/31/2008 6:05:55 PM

    Worse than SARS? Not even close. SARS is a highly contagious respiratory virus; TB is a slow-growing bacteria that a healthy body often marshalls an effective defense against. It takes only days to contract and die of SARS - it takes years to contract and die of TB, years when therapies can be very effectively mounted against TB.

    TB becomes an issue for people with poor health, poor ventilation, poor nutrition, and compromised immune systems, which is why it is such a problem in third-world countries, but rare in industrialized countries.

    Any time a germ develops resistance it is cause for concern, but XDR-TB is rare, and will remain so. Yes, we need to be vigilant, but media hype is completely uncalled for.

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