10 BIG THINKERS FOR BIG BUSINESS

Revolution's biggest challenge, says Case, is to "empower" consumers, who will increasingly control more of their health-care dollars through price-sensitive tools such as health-care savings accounts. Given the choice, consumers might pay for "wellness" services like nutrition advice and exercise, Case says. There are plenty of naysayers, but Case says he's unbothered by them. He says Revolution isn't his attempt to "prove something" after his travails at AOL. "It's about trying to make a difference." If he succeeds, Case will have done both.

--Karen Breslau

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