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Could Gene Therapy Treat Male Infertility?

 

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Still, this new insight opens the possibility of treating male infertility with genetic therapy, where doctors could plausibly target particular genes, like Jhdm2a, in order to restore normal sperm function. A new treatment that alters sperm shape and count could have wide applicability in male infertility treatment as those factors account for about 40 percent of cases. This would be a welcome addition to the three treatments now used for male infertility: assisted reproduction, like in-vitro fertilization; surgery to remove varicose veins in the penis or testes, and drug therapy to correct a hormonal imbalance. Success rates are relatively low for these treatments; assisted reproductive technology, for example, has a success rate that hovers around 50 percent.
One of the most challenging obstacles to treating male infertility, however, may not even be medical. The social stigma that exists around male infertility deters men from seeking out treatment in the first place. In surveys, men report feeling "emasculated" or like "losers." Research like this, which gets to the serious science of male infertility, may help dispel such associations.

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Member Comments

  • Posted By: pinkiroy @ 10/20/2007 2:45:14 AM

    It is indeed sad to learn that even after so much advancement in the arena of Science and technology, this area was most un-researched, most untouched....Anyway, kudos to the team of scientists who have ultimately found a solution to the problem of male infertility.

  • Posted By: pinkiroy @ 10/20/2007 2:42:44 AM

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  • Posted By: jvazq25 @ 10/18/2007 6:01:35 PM

    Wow, incredible to hear people say these kinds of things. Hopefully neither of you come down with health problems and if you do it'll only be fitting for you dont know what its like to be dying. And maybe just maybe infertile men want to have what is called a legacy (their own children), not that theres anything wrong with adopting.

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