Known as the spice island, Zanzibar is a beguiling mix of Arabic, African and Indian cultures. From Stone Town's tiny streets to isolated coral reefs, this paradise off the coast of Tanzania draws anyone looking to chill. Stone Town is the best place to start. Stay at the seafront Serena Inn, where rooms overlook the Indian Ocean and the interior celebrates the island's Persian and European influences (from $285 per person; serenahotels.com). Set aside an afternoon to get lost in the city's labyrinth of houses, bazaars and courtyards.
Head out of town to enjoy the powdery white beaches. Each of the nine rooms at Matemwe Bungalows features a porch with huge hammocks and a sumptuous bath. Meals are served on the patio, and guests can relax at the two pools or sip a dawa (Swahili for medicine) cocktail of vodka, lime and sugar at the beach bar ($230 per person in low season; matemwe.com).
Suites at the Zamani Zanzibar Kempinski offer grand views of the ocean. Guests can enjoy floral foot baths at the spa or go on snorkeling expeditions (from $250; www.kempin ski-zanzibar.com). No wonder Zanzibar's unofficial motto is "Hakuna matata"—Swahili for "No problem."