Urdu, Mandarin, Haitian Creole... By the thousands each week, they pass through the doors of Elmhurst Hospital in Queens, the borough of New York City that contains Kennedy airport and is home to perhaps a greater diversity of foreign-born immigrants than any comparable community in the nation or the world.

Spanish, Korean, Albanian... A broken bone is the same in any language, but not so diabetes or hypertension--abstractions for which many people do not have words. The very concept of organic illness varies from culture to culture. If you were brought up to believe that your symptoms arise from sorcery or from something you did in a previous life, you might not grasp the necessity for a course of chemotherapy whose most immediate and obvious effect will be to make you feel a hundred times worse. And if well-educated Americans sometimes find it hard to keep track of the complicated regimen of medications for, say, heart failure and diabetes together, it surely is no easier for a Pashto speaker relying on her grandson to explain how to measure her blood sugar. There are barriers to communication even among people who speak the same language, like a white AIDS specialist and the African-American patient who knows that the only people he sees dying of the disease are black.

The languages were different--Polish, Yiddish or Italian--but even a century ago, poor immigrant patients and upper-middle-class physicians faced each other suspiciously across a vast cultural gap. But probably never in our history has this country had to absorb so many newcomers from such a diversity of cultures, and medicine, which touches so intimately on their lives, has never been more specialized and technological. "Hmong [a Laotian ethnic group with a pastoral culture] will smile and nod when they're with the doctor, but they have no intention of taking the pills," says Sa Vang, a fourth-year medical student at the University of California, Davis, whose parents came to the United States in 1979. "My grandmother would only take her blood-pressure medication when she had a headache." Vang has seen this happen many times in her community: patients who take their pills in response to a specific symptom, which may or may not be related to the condition the drugs are supposed to treat. The patient doesn't want to offend the doctor, so he says he's been taking his medicine; the condition hasn't improved, so the doctor increases the dosage, to the point where the patient starts to experience unwanted side effects. The result: "Patients think the doctors don't know what they're doing."

The best-documented case of such misunderstandings involved Lia Lee, the daughter of a Hmong family in Merced County, Calif., in the late 1980s. When she was 3 months old, she fainted on hearing the sound of a door slamming. Doctors assumed the seizures she suffered after that were from epilepsy, but her parents provided their own diagnosis, the temporary disappearance of her soul out of her body, a condition whose name translates as "the spirit catches you and you fall down" (which was the title of an excellent book by Anne Fadiman on Lia's case). Whether modern medicine could have controlled her epilepsy is unknown; what Fadiman found was that her highly competent and dedicated doctors prescribed more than a dozen different drugs in various dosages and combinations that changed 23 times in four years. Her well-meaning parents, illiterate even in Hmong, followed the doctors' orders only sporadically, but sent away to Thailand for sacred amulets, and changed Lia's name to fool the evil spirits--a plan that failed, according to her mother, because the doctors insisted on calling her Lia. Four years after her first symptoms, she suffered a massive seizure that left her in a persistent vegetative state, where she remains today. She is 22.

Few other groups have as great a cultural distance to traverse as the Hmong, but even native-born Americans may suffer from poor communication with their doctors. Minorities often carry a burden of suspicion with them into the examination room, as shown in a RAND Corp. study this year; 53 percent of African-Americans surveyed agreed that there is a drug to cure AIDS, but poor people aren't being told about it, and nearly one in six believed that AIDS was created by government scientists to control the black population. Lead researcher Laura Bogart noted that men who held those beliefs were significantly less likely to use condoms.

"When I was in medical school, there was lots of talk about [racial] disparities in health care, but it focused on access," says Dr. Maren Grainger-Monsen, director of the Bioethics in Film Program at Stanford. "Then we learned that minorities with equal insurance and access still had drastically worse outcomes in cardiac surgery and lung cancer." Grainger-Monsen believes the "shocking" disparity can be attributed, in large part, to cultural differences and failures of communication, which afflict minorities. Her new film, "Hold Your Breath," recounts the case of Mohammad Kochi, an Afghan immigrant who was treated in California for stomach cancer. After his surgery, doctors recommended chemo- therapy, but Kochi refused to undergo an unpleasant treatment that might not work. His real objection emerged much later: his doctor had prescribed a continuous intravenous infusion of chemotherapy, which would have minimized the side effects. But Kochi was a devout Muslim who prayed five times a day and could not let foreign fluids enter his body after he had cleansed himself for prayer--a prohibition that he believed extended to an IV drip. He never knew there were other ways to receive chemotherapy--and by the time this got straightened out, it was too late to help.

A trained medical interpreter might have gotten to the root of Kochi's problem sooner, but he had relied on one of his daughters, who had her own ideas about which information her father should receive. When his doctor told him that he still had cancer after the surgery, she refused to translate that information, fearing it would upset him. Dr. Joseph Betancourt, director of multicultural education at Massachusetts General Hospital, recalls how as a 7-year-old he was asked to serve as the intermediary between a doctor and his Spanish-speaking grandmother from Puerto Rico. Simple ignorance of medical terms was compounded by embarrassment; his grandmother was suffering from uterine cancer. "We still see kids acting as the cultural brokers for their families," says Betancourt, "but it's no way to run a hospital."

The medical profession has its own traditions, of course, and humility did not always rank high among them. But physicians increasingly realize that, simple human dignity aside, respecting patients' cultural beliefs can avoid tragedies like Lia Lee's. Fadiman's book on the case is now assigned in many medical schools; at Yale, incoming students discuss it on the very first day of class. And more than 100 medical programs use the saga of Kochi to help teach "cultural competence." As Sa Vang shows by her own example, many of the problems will lessen as immigrants assimilate. It would be unthinkable for her to do as her parents did, when they sacrificed goats and chickens to cure her grandmother. She knows that disease is not caused by evil spirits snatching the soul out of the body. Her husband doesn't really believe that either, but neither does he let their two young sons attend funerals, where the evil spirits are especially active. And Sa Vang, the medical student, doesn't object.

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