'Big Mouth' Season 4 Cast: Who Voices the Characters on the Netflix Series?

Big Mouth Season 4 is airing now on Netflix, the first season after the animated show made a major casting decision. The series has joined shows like The Simpsons in pledging that it will no longer have white actors playing characters of color. This means that Jenny Slate will no longer play Missy, who will be voiced by a new actor, who takes over towards the end of the current season.

One thing that has not changed in Season 4 is the calibre of guest stars the series has managed to bring in. Among those making guest appearances are Seth Rogen, Maria Bamford and the British tones of John Oliver.

Who are the new cast members in Big Mouth Season 4?

Ayo Edebiri - Missy Foreman-Greenwald

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Ayo Edebiri takes over from Jenny Slate as the voice of Missy towards the end of 'Big Mouth' Season 4. Netflix

Jenny Slate will no longer voice Missy, with comedy writer and actor Ayo Edebiri taking the role—though slate will still voice the character for all but the last two episodes. Best known as a writer of NBC comedy Sunnyside (who is also working on writing Big Mouth Season 5), the actor also starred in indie movie Cicada this year.

Maria Bamford - Tito the Anxiety Mosquito

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Maria Bamford voices a mosquito in 'Big Mouth' Season 4. Netflix

A beloved comedian among other comedians, Bamford is best known to the general public for her surreal Netflix comedy Lady Dynamite. She has previously voiced characters, however, for BoJack Horseman, Adventure Time and The Legend of Korra and starred in Arrested Development and Fresh Off the Boat.

John Oliver - Harry

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John Oliver's character in 'Big Mouth'. Netflix

Best known for his critically-acclaimed late-night show Last Week Tonight with John Oliver, as an actor he had a recurring role on Community and was part of the voice casts of the 2019 Lion King remake and The Smurfs movies. In Big Mouth, he is playing camp counsellor Harry.

Seth Rogen - Seth Goldman

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Seth Rogen's (left) character in 'Big Mouth'. Netflix

Another Lion King alum, Seth Rogen voiced Pumbaa in the 'live-action' movie, stars in movies like Superbad, Pineapple Express and this year's An American Pickle. He plays a new character the cast meets at camp in Season 4 of Big Mouth.

Josie Totah - Natalie

After being the breakout star of Peacock's Saved by the Bell reboot, Josie Totah plays Natalie, a transgender camper.

Also cameoing in Big Mouth Season 4 are:

  • Sterling K Brown (This Is Us) - Michael Angelo, an artistic type who Jessi meets in New York
  • Zach Galifinakis (The Hangover) - The Gratitoad, a toad that loves to show gratitude
  • Quinta Brunson (A Black Lady Sketch Show) and Lena Waithe (Master of None) - Quinta and Lena, Missy's Atlanta cousins
  • Anna Konkle and Maya Erskine (PEN15) - Izzy and Misha, seventh grade girls who Nick and Andrew meet at the start of the school year
  • Paul Giamatti (Sideways), whose role has not officially been announced yet

Who Returns to Big Mouth Season 3 Cast?

  • Nick Kroll (Kroll Show) - Nick Birch/Maury the Hormone Monster/Coach Steve
  • John Mulaney (Saturday Night Live) - Andrew Glouberman/Various Characters
  • Jessi Klein (Inside Amy Schumer) - Jessi Glaser
  • Jason Mantzoukas (The Good Place) - Jay Bilzerian/Various Characters
  • Fred Armisen (Portlandia) - Elliott Birch/Various Characters
  • Maya Rudolph (Bridesmaids) - Diane Birch/Connie the Hormone Monster/Various Characters
  • Jordan Peele (Key and Peele) - Ghost of Duke Ellington/Various Characters

Big Mouth Season 4 is streaming now on Netflix.