Brangelina: George Clooney, Adele and More React to Hollywood Divorce

Brad and Angelina
Angelina Jolie and Brad Pitt attend an official screening of "By the Sea" in New York, November 3, 2015. The stars' split has shocked Hollywood friends. Robin Marchant/Getty

The split that rocked the world took place Tuesday as Angelina Jolie filed for divorce from her husband Brad Pitt after only two years of marriage but over a decade together.

In a statement, Jolie said she had filed for divorce for the "health of the family," referring to the couple's six children together.

As news of Brangelina's demise spread wide and far late Tuesday, stars including Pitt's friend George Clooney and singer Adele weighed in on the split.

Clooney, who starred alongside Pitt in the Ocean's Eleven movies, learned about the divorce while being interviewed by CNN. "That's a sad story and unfortunate for a family," he said. "I feel very sorry to hear that. This is the first I've heard of it."

Watch below:

So George Clooney found out about #Brangelina split from CNN:

— Tufayel Ahmed (@tufayel) September 21, 2016

British music sensation Adele, currently on tour in the U.S., had a typically Adele response to the divorce: she dedicated her concert at New York's Madison Square Garden Tuesday night to Brangelina. "I need to address the elephant in the room," she said. "It's the end of an era."

Jolie's father Jon Voight told Inside Edition the news is "very sad." He added: "Something very serious must have happened for Angie to make a decision like this."

Other stars, including Chrissy Teigen and Frozen actor Josh Gad, shared their shocked reactions on Twitter:

Brad and Angelina. How am I supposed to go to work today ?

— christine teigen (@chrissyteigen) September 20, 2016

Before we get too cavalier about it, let's remember that #brangelina was possibly the only thing still holding the USA together.

— Josh Gad (@joshgad) September 20, 2016

I blame Donald Trump. #Brangelina

— Piers Morgan (@piersmorgan) September 20, 2016

Tower of Terror! Eggo! Skittles! Brad Pitt! I don't know why ANY of them are trending but I'm running to my basement. It's over.

— Patton Oswalt (@pattonoswalt) September 20, 2016

WTF? Brad and Angelina?! I'm crushed.

— Alyssa Milano (@Alyssa_Milano) September 20, 2016