Watch Alexandria Ocasio-Cortez on 'Desus and Mero' Showtime Premiere

Desus Nice and The Kid Mero—mostly known as Desus and Mero—will premiere their highly anticipated new late-night show, aptly titled Desus and Mero on Showtime, on Thursday.

The curators of the beloved podcast, The Bodega Boys, previously helmed the weekly Viceland late-night show similarly titled after them. The comedians offered their hilarious rapid-fire hot takes on an array of social and political topics, interviewing dozens of public figures. They ranged from MSNBC's Rachel Maddow to rapper French Montana.

The premiere of their newest format will feature fellow Bronx native, New York Representative Alexandria Ocasio-Cortez, whose commentary on Twitter often ruffles the feathers of her political opponents.

While details of the premiere episode and Ocasio-Cortez's appearance have been kept under wraps, fans should at least expect to hear a heaping of the hosts notable "yerp," a greeting commonly used in their hometown of the Bronx.

Appearing on Late Night with Seth Meyers on Tuesday, Desus and Mero gushed over their experience interviewing the outspoken Ocasio-Cortez on Capitol Hill. "We definitely did [bring the Bronx out of her]," said Mero. "She just leaned out of office door and delivered the heartiest, 'Yeeerrrrpppp,' I've ever heard."

They also noted the impact she already seemed to have on Washington D.C. "It's because Congress is so antiquated, and rules, stodgy, and now you've got a New Yorker," Desus said. "And you know us New Yorkers, we like to be very frank and very straight. So they're not used to her."

He added: "She's a little rough around the edges but I think she's getting stuff done and it's making them a little nervous."

Of course, the comedian's arrival at the nation's capital didn't come without a few hiccups, including a visit from capital police requesting proof of their documents to film.

"What's funny is—and I do not know if most people know this—but [Vice President] Mike Pence has a brother that's a representative or something. And surprisingly we're filming in front of his office and all of a sudden the capital police comes and asks us for our film permits," Desus said. "Ya snitch!"

"He's [on the phone with Mike] like, 'Desus and Mero are here, they're gonna slander us. Tell mother. Tell mother to call'," Mero joked. "Shout out to nepotism."

Viewers will likely see more hilarious banter on the Showtime series as the guys discuss an array of topics ranging from pop culture, sports, music, politics and more.

Desus and Mero on Showtime premieres at 11 p.m. ET on Thursday.