What Is 22q Syndrome? #HeyJustin Trends as Man With Disorder Asks for Millions of Hellos

A Massachusetts-based content creator and activist was the focus of a Twitter trending topic on Monday. The trend was in relation to a video he released raising awareness of his syndrome while calling on users of the site to say hello and share his hashtag.

Boston resident Justin Gigliotti, who uses the handle @syndrome22q1, received a wave of support from users of the social network after uploading the short 29-second clip to his profile that was seeking "hellos from millions of people from around the world."

The term #HeyJustin became a trending topic and had been used over 18,000 times as of Tuesday morning. His tweet attracted over 13,000 responses.

Gigliotti explained in the video upload that he had a disability called 22q syndrome and he was "curious" to see how many people would respond to his request. He added: It would make my day... it would make my heart happy, it would make me happy."

- I have a disability which is called 22q Syndrome
Even tho i am Different i am curious to see how many people watching this will say hello to me using the hashtag #HeyJustin id love to get hellos from millions of people from around the world. Retweet! pic.twitter.com/ZBdkZ7wwkv

— Justin G (@syndrome22q1) March 1, 2021

Gigliotti, who is also known on his accounts as Justin G, has repeatedly used the profile for similar social campaigns over the past month, promoting hashtags centered around his name and tagging profiles to signal-boost his account and raise awareness.

The Mayo Clinic, a Minnesota-based healthcare and research nonprofit, explains that the condition is called 22q11.2 deletion syndrome, or DiGeorge syndrome.

The disorder is caused when a part of the human chromosome 22 is missing and usually occurs "as a random event" in fetal development, or in human sperm or eggs.

The syndrome can lead to a variety of medical problems, including "heart defects, poor immune system function, a cleft palate, complications related to low levels of calcium in the blood, and delayed development with behavioral and emotional problems."

Gigliotti YouTube's account, which does not appear to have been active in the past year, has gained about 58,000 views since being launched in 2016, analytics show.

The profile contains videos discussing the syndrome, which he calls 22q, and uploads have sought the attention of comedian and talk show host Ellen DeGeneres.

DeGeneres replied to one of Gigliotti's posts in 2019 after he called for people to send Christmas wishes with the hashtag #MerryChristmasJustin.

❤️ #MerryChristmasJustin https://t.co/Y4spGoAY3A

— Ellen DeGeneres (@TheEllenShow) November 23, 2019

In a video in February 2017, Gigliotti said he endured multiple heart surgeries relating to his syndrome, but that would not get in the way of his life ambitions.

He stated: "If you have a disability or if you have a syndrome that shouldn't stop you from doing what you want to do, whether it's making videos or having that awesome job. For me, having 22q syndrome is not going to stop me from making music, that is not going to stop me from putting videos up on YouTube. It's not going to stop me."

Justin G
Justin G tweeted on March 1, 2021: "I have a disability which is called 22q Syndrome. Even tho I am different I am curious to see how many people watching this will say hello to me using the hashtag #HeyJustin id love to get hellos from millions of people from around the world." Screenshot/@syndrome22q1