Patrick Dempsey, Sexiest Juggler Alive!

Dr. McDreamy, Patrick Dempsey, stars in the romantic comedy "Made of Honor," which is like "My Best Friend's Wedding," with Dempsey in the Julia Roberts role. He spoke to Ramin Setoodeh.

Hi, Patrick. How are you doing?
I'm good. I'm multitasking, trying to get my script organized, with all these rewrites, and listening to NPR—let me shut that off.

Are you on the "Grey's Anatomy" set?
I am.

Are you in scrubs right now?
I am indeed.

This new movie's a slapstick comedy.
I like the old classic comedies—Cary Grant could be a great romantic lead and do slapstick. That's something we thought about. So the director asked me if I could juggle.

Didn't you win a juggling contest when you were a kid?
I came in second in the international jugglers' junior division when I was 12 or 13.

Did you get a trophy?
I got a plaque. I'm sure my mother has it somewhere.

I heard there was a scene cut from the movie with you in a wedding dress.
I don't look good in a dress. I don't have the shoulders.

And another that was cut was a locker-room nude scene.
Yeah, the director Paul [Weiland], being European, said, "Oh come on, let's be nude. Everybody get naked." And I said, "OK, we'll do that." But it didn't make the movie, because they wanted to keep it PG-13.

Maybe it'll be a DVD extra.
I wouldn't be surprised. But believe me, mystery is a better thing than reality.

You must be stalked by women everywhere.
Because of the success of "Enchanted," I get the little ones, and the grandmothers, too. The little girls want to know where Giselle is. The grandmothers are very sweet.

What do the 20-year-olds want?
Other things.

I brought my mother to the premiere of "Enchanted" and I think she'd leave my father for you. Is your wife a good sport?
She has a great sense of humor and she keeps me in line.

So you don't look in the mirror and think, God, I'm McDreamy.
God. I wish I could be.

Did you know Hillary Clinton's a big fan of "Grey's Anatomy"?
Yeah, I heard that. It's funny because I spoke to her a few nights ago and she wanted to know when the show was coming back on. And this is in the midst of a big fund-raiser with superdelegates all around. I didn't get a chance to tell her to prepare for "Made of Honor." There is a moment about Bill in there; had I known she was so into the show, I would've taken it out.