Premier League Preview, Odds—Can Chelsea or Liverpool Dethrone Manchester City?

Manchester City are overwhelming favorites to retain their Premier League crown in the 2021/22 campaign.

The new top-flight season gets underway when newly-promoted Brentford host Arsenal on Friday evening.

Oddsmaker SBK Sportsbook has previewed the upcoming Premier League season where Man City (4/5) are heavily backed to win a fourth title in five years.

City have strengthened their already star-studded squad with the £100 million ($138m) signing of Jack Grealish.

The England midfielder joined for a Premier League record fee and looks set to play an integral role under Pep Guardiola.

Chelsea (5/1) are the closest challengers to dethrone City having beaten their rivals in the Champions League final last season.

Thomas Tuchel's side could be an even more daunting prospect when they finalize a club-record £97.5 million ($135m) deal for Romelu Lukaku.

Liverpool, who have a fit-again Virgil van Dijk back in defence, are 6/1 to recreate their 2019/20 Premier League-winning season, despite a quiet summer transfer window.

Manchester United, despite the signing of Raphael Varane, are an outside shout at 9/1, while Leicester and Arsenal are priced at 70/1.

Premier League winner odds from SBK

Manchester City - 4/5
Chelsea - 5/1
Liverpool - 6/1
Manchester United - 9/1
Leicester - 70/1
Arsenal - 70/1
Tottenham - 80/1
Leeds - 175/1

Top 4 favorites

Manchester City (1/16), Chelsea (1/4), Liverpool (1/3) and Manchester United (4/11) are the favorites to make up the top four this season.

Elsewhere, Leicester, who have narrowly missed out on a top-four finish for the past two seasons, along with Tottenham and Arsenal are fancied at 9/2 to qualify for Champions League football.

Marcelo Bielsa's Leeds wowed the Premier League with their attacking style of play last term and are audaciously priced at 11/1 to break into the top four.

Manchester City - 1/16
Chelsea - 1/4
Liverpool - 1/3
Manchester United - 4/11
Arsenal, Leicester, Tottenham - 9/2
Leeds - 11/1
West Ham - 15/1
Aston Villa - 25/1

Top six chasers

Leicester (1/1) are backed to secure a third successive top six finish under Brendan Rodgers this season—and they are expected to battle it out with Tottenham and Arsenal (both 6/5).

Spurs and the Gunners finished in seventh and eighth, respectively, last term, but are good bets to bounce back.

Everton have been given 4/1 odds of finishing in the top six, despite managing to only sign Asmir Begovic, Andros Townsend and Demarai Gray so far this summer.

Leeds and West Ham (both 5/1) trail Everton with Aston Villa (11/2) a bold shout following the exciting summer arrivals of Danny Ings, Emi Buendia, Leon Bailey and Ashley Young.

Manchester City, Chelsea, Liverpool, Manchester United - 1/100
Leicester - 1/1
Tottenham, Arsenal - 6/5
Everton - 4/1
Leeds, West Ham - 5/1
Aston Villa - 11/2
Brighton - 9/1
Wolves - 10/1
Southampton - 15/1

Premier League preview and odds of EPL
Liverpool, Manchester City and Chelsea will all be battling for the Premier League title this season. Getty Images

Relegation candidates

Unsurprisingly, the three newly-promoted clubs—Norwich (20/21), Watford (1/1) and Brentford (17/2)—have the shortest odds to make an immediate return to the Championship.

Next to them is Crystal Palace (17/10) who will not have the stability of Roy Hodgson to rely on this season. Instead, Arsenal legend Patrick Vieira is taking the reins in his first managerial job in the Premier League.

Burnley seem to always find a way to avoid relegation as they enter their sixth Premier League campaign under Sean Dyche.

However, they are priced at 17/8 with Newcastle (14/5) and Southampton (3/1) following closely behind.

Norwich - 20/21
Watford - 1/1
Brentford - 17/2
Crystal Palace - 17/10
Burnley - 17/8
Newcastle 14/5
Southampton - 3/1
Wolves - 6/1
Aston Villa - 9/1
Brighton - 10/1

Golden Boot winner odds

Harry Kane is priced at 4/1 to win a fourth Premier League Golden Boot.

The Tottenham striker topped the scoring charts with 23 goals last season, a feat that is made more impressive when you consider Spurs' final league position.

Liverpool talisman Mohamed Salah was just one goal behind Kane and is the second favorite to claim the award at 11/2.

Outside shouts include Salah's Liverpool teammates Diogo Jota and Sadio Mane (both 22/1), along with Aston Villa new boy Danny Ings (23/1).

Bruno Fernandes, who finished on 18 Premier League goals last term, is surprisingly a long shot at 25/1 to win a first-ever Golden Boot.

Harry Kane - 4/1
Mohamed Salah - 11/2
Diogo Jota, Sadio Mane - 22/1
Danny Ings - 23/1
Pierre-Emerick Aubameyang, Jamie Vardy, Raheem Sterling - 24/1
Bruno Fernandes, Timo Werner - 25/1
Dominic Calvert-Lewin - 26/1

First manager to leave a job

The Watford job is a precarious one to have with the club employing six managers in the past four years.

So it is no surprise to see Xisco Munoz (5/1) as the favorite to become the first manager to lose his job.

Vieira is priced at 11/2 to leave his role prematurely, while Steve Bruce (9/1) could pay the price if Newcastle fail to get off to a good start.

Xisco Munoz - 5/1
Patrick Vieira - 11/2
Steve Bruce - 9/1
Graham Potter - 10/1
Mikel Arteta, Ralph Hasenhuttl - 12/1
Rafael Benitez, Daniel Farke, Bruno Lage - 16/1
Thomas Frank - 18/1