Thursday Night Football: Bengals vs Browns Kickoff Time, Live Stream, TV Channel

Week 2 of the NFL season begins on Thursday in Cleveland, where the Browns welcome AFC North rivals Cincinnati Bengals as the league marks a major milestone.

The matchup between the NFL's two current Ohio franchises is a nod to the role the state played in the formation of the league, which was founded as the American Professional Football Association in Canton exactly 100 years ago today and originally featured four Ohio-based teams. It was subsequently renamed to the NFL.

Here's all you need to know ahead of Thursday Night Football.

• Kickoff time—The Browns host the Bengals at FirstEnergy Stadium in Cleveland, Ohio. Kickoff is scheduled for 8:20 p.m. ET on Thursday, September 17.
• TV channel—NFL Network
• Live stream—NFL Network website and NFL Network app on connected devices, Yahoo Sports app and fuboTV.
• Odds—The Browns are a six-point favorite with DraftKings and 9/10 to cover the spread, while the over/under line for total points scored is set at 30.5. In moneyline terms, Cleveland is a 2/5 favorite, while Cincinnati is a 43/20 underdog.
• Series history—The Browns have won three of the last four meetings against the Bengals, but Cincinnati leads the all-time series 51-42.

The Bengals and the Browns both ushered in new eras in Week 1, with Cincinnati handing the keys to the offense to first overall draft pick Joe Burrow, while Kevin Stefanski became Cleveland's fourth head coach in as many years.

In his NFL debut, Burrow completed 23 of his 36 passes for 193 yards, adding 46 rushing yards and one score on the ground as the Bengals lost 16-13 to the Los Angeles Chargers.

The Browns, meanwhile, were on the receiving end of a 38-6 shellacking in Baltimore in the most lopsided game of the week.

After throwing a costly interception to thwart Cincinnati's chances to take the lead late in the game, Burrow drove the Bengals down the field again only for Randy Bullock to miss a 31-yard field goal that would have forced the game into overtime.

Bullock said he suffered a cramp in his left calf as he attempted the kick and the Bengals picked up Austin Seibert off waivers earlier this week, just a day after the latter was cut by Cleveland after missing both of his attempts in the Browns loss to Baltimore.

The Browns won't be the last team to lose to the Ravens this season, but the manner of the defeat hinted at familiar issues in Cleveland. Baker Mayfield's figures were similar to Burrow's, as the Cleveland quarterback finished with 189 passing yards, one touchdown and one interception for 65.0 passer rating that ranked 31st out of 32 quarterbacks in Week 1 and marginally below Burrow's 66.1.

Two years removed from being selected with the first overall pick of the 2018 Draft, Mayfield's regression is increasingly becoming a concern and reignited the debate over the lack of chemistry between him and star wideout Odell Beckham Jr., who only had three catches for 22 yards on 10 targets in Week 1.

On paper at least, the Bengals are the ideal team for Mayfield to get back on track as the former Oklahoma star has a 100.5 rating and 10 passing touchdowns in four games against the Bengals, the most against any of the teams he's faced since making his NFL debut two seasons ago.

Even with Beckham and Mayfield struggling, the Browns still produced 306 yards of total offense with Kareem Hunt and Nick Chubb combining for 132 yards rushing and the running game could be key for both teams on Thursday night.

Hunt averages 140.3 yards from scrimmage per game in three career games on Thursday Night Football and has scored a touchdown in five of his last six primetime games, while Chubb has averaged 104 yards from scrimmage per game in his last five primetime games. Meanwhile, Bengals running back Joe Mixon has racked up at least 175 yards from scrimmage and a rushing touchdown in his last two games against Cleveland and was the pick of Cincinnati offense, rushing for 69 yards over 19 carries.