The ad depicts Biden as an individual who has been "shaped by both tragedy and love."
In his tweet, Steve Guest, the Rapid Response Director of the Republican National Committee, wrote, "Hey Joe Biden, are you still a Redskins fan?"
Biden, 76, had three children with his first wife Neila Hunter and one with his second wife, Jill Biden.
If not for this disease, our present might have looked very different.
Joe Biden appears to refute Maureen Dowd.
In a moving interview, the vice president suggests he isn't emotionally ready to run for president.
Condolences pour in on social media while the White House creates an "In Memory of Beau Biden" page.
Beau Biden had been battling brain cancer.