The Philadelphia Eagles will be the first team to pick of those who have made the playoffs, followed by the Buffalo Bills, New England Patriots and New Orleans Saints.
Home field was not kind to three of the four NFL teams that hosted games over the weekend. The four teams that had byes—Baltimore, Kansas City, San Francisco and Green Bay—will all host games in the divisional round.
The Texans look to reach the divisional round for the first time since 2016, while the Bills search for a first wild-card round win since 1995.
There were only three NFL games on Saturday, but they went a long way to help determine who's in the playoffs, who is out and which teams clinched division titles to host a first round game.
The AFC East title is on the line as the two divisional rivals meet in Foxborough, with the Patriots looking for a seventh straight win over the Bills.
Green Bay, New England, Seattle, Buffalo and San Francisco all clinched a playoff spot in Week 15 and four berths are still up for grabs.
Buffalo could clinch a playoff spot with a win in Pittsburgh, while the Steelers can leapfrog the Bills in the race for a wildcard spot.
New Orleans is the only team to have qualified for the playoffs so far, but Baltimore, New England, Kansas City, San Francisco and Seattle can join it on Sunday.
The Baltimore Ravens took control of the AFC with a 20-17 over San Francisco, which saw the 49ers slip to fifth in the NFC.
The New Orleans Saints became the first team to clinch a playoff spot this season with a 26-18 win over the Atlanta Falcons on Thanksgiving.
Jason Garrett is under pressure from franchise owner Jerry Jones as the 6-5 Cowboys host the 8-3 Bills on Thursday.
The NFL's triple-header on Thanksgiving last year saw the fourth most wagers placed on a sporting event in the U.S. in 2018.
The NFL's Thanksgiving tradition continues this year, as the Lions host the Bears and the Cowboys welcome the Bills, while the Saints take on the Falcons.
Week 13 features three games on Thanksgiving Day, while the New England Patriots face the Texans in Houston on "Sunday Night Football."
The Patriots and the Chiefs look set to win their divisions, while the Chargers and Browns face a battle to reach the playoffs.
The Lions are looking for a first win in preseason when they host the Bills on Friday night, while Buffalo aims for a third straight victory.
The Steelers' wide receiver described rumors of a move to the Bills as "fake news."
A video of the incident showed blood stains covering the hallway where the altercation unfolded.
The Jaguars beat the Bills in Florida.
There's no Sunday Night Football, but still plenty to watch.
"Gronk" doesn't usually do this kind of thing.
The Bills are worth watching this season.
There's a lot of very poor football and a glut of very average teams. And that is making it tremendous fun to watch.