The aim is to test the drug as a treatment for mild COVID symptoms, not as an alternative to vaccination, according to the Duke Clinical Research Institute.
Moderna's vaccine candidate will be trialed at 89 clinical research sites in the U.S.
The vaccine to protect against COVID-19 will enter a Phase 3 efficacy trial at the end of July.
"We recognize the importance of answering the scientific question of whether hydroxychloroquine will be beneficial for patients with COVID-19 disease," said John Tsai, Novartis chief medical officer.
David C. Fajgenbaum was diagnosed with Castleman disease in 2010 and failed to respond to the only approved drug.
Researchers hope the drug will reduce reliance on injections and help prevent life-changing complications.
In general, these kinds of small studies are done to make sure a treatment is safe. To figure out whether it really works, more studies have to be done.
Clinical trials on a prospective type 1 immunization are set to begin next year.
When should cancer patients consider clinical trials? Where should they look? How should they evaluate options?
Some clinical trial experiences are so terrible, it's "almost as bad as dealing with Comcast or the worst airline."
Scientists have started a clinical trial to see whether a vaccine could reduce high cholesterol, which can lead to heart disease and other complications.
Dravet syndrome causes drug-resistant seizures and children rarely survive to adulthood.
Police say the man drugged and raped at least 100 women, but the total number could be much higher.