The two Serie A arch-rivals meet on Sunday night in Milan with the hosts looking to extend their perfect record.
The defending Serie A champions look to go back at the top of the table when they play newly promoted Hellas Verona on Saturday.
Two of the Champions League dark horses meet on Tuesday afternoon when Atletico Madrid hosts Juventus.
Juventus looks for a third consecutive win when in travels to Florence to face Fiorentina on Saturday.
The two main title favorites go head-to-head on Saturday as Juventus hosts Napoli in Turin with both sides looking for a second straight win.
Serie A returns this weekend, as Juventus begins a quest for a ninth consecutive after appointing former Chelsea boss Maurizio Sarri.
Juventus is the bookmakers' season to win a ninth league title in a row, but Napoli and Inter Milan have reasons to be optimistic.
Las Vegas investigators confirmed on Thursday that they issued a warrant to get a DNA sample of Cristiano Ronaldo to determine if it pairs with the dress of his rape accuser.
Kathryn Mayorga, who met the footballer in Las Vegas in the summer of 2009, has accused him of rape.
The Portuguese icon was accused by Kathryn Mayorga in a long interview with German magazine Der Spiegel.
Ronaldo will make his Allianz Stadium debut on Saturday, when Juventus take on Lazio.
Ronaldo's contract with Real Madrid expires in 2021, but he's reportedly decided to leave Spain.
Current Ballon d'Or winner has been linked with a shock move away from Real Madrid this summer.
The five-time Ballon d'Or winner will reportedly earn $35 million every year in Italy.
The U.S. president steered clear of confirming a trip to Moscow, so he decided to talk about the World Cup instead.
The 411 on this summer's biggest sporting event.
Real Madrid and Liverpool will pin their respective hopes on Ronaldo and Salah on Saturday.
From soccer to tennis to basketball, it's clear that it pays to be gifted athletically.
"Now, 100 million euros is nothing. It was a lot when I paid for Cristiano Ronaldo."
The Real Madrid striker scored again—but this one, he says, is his greatest ever.
Ernesto Valverde's team already has an 11-point lead on Real heading into the game.