The travel impacts come as many questions still remain about the highly mutated variant and how it may be compared to other strains.
Governor Ron DeSantis vowed on Monday to keep fighting the federal agency over the COVID-19 mandates.
In April, the state of Florida sued the CDC, saying that Congress had never granted it the authority to regulate health and safety standards on cruise ships.
The first U.S. cruise in 15 months sets off Saturday as the industry hopes to make a comeback. Florida law blocked the ship from requiring proof of vaccination.
"The cruise industry is essential to our state's economy and keeping it shut down until November would be devastating to the men and women who rely on the cruise lines to provide for themselves and their families," the governor said Friday.
"It is unconscionable for the CDC to move forward on a plan to resume operations given the ongoing risks," read a Friday letter from two Democrat lawmakers.
"There's all kinds of ways we can use immunity to our advantage but nobody's admitting it," Sen. Rand Paul (R-Ky.) said on Sunday while suggesting that those who have recovered from COVID-19 work with the elderly or vulnerable groups in the service industry.
"This is very discouraging news and not what we had hoped for," said UnCruise CEO Dan Blanchard on Wednesday.
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While Carnival Corporation confirmed it will "fully cooperate" with the investigation, Carnival Cruise Line announced it will resume voyages on eight ships from Miami, Port Canaveral and Galveston.
As Carnival seeks $6 billion in funding to help with financial fallout caused by the COVID-19 pandemic, SEC filings on Monday showed that over 6,000 people were still sailing on ships owned by the company.
The 'Real Time' host made a case for ending the cruise ship industry Friday night in an unusually quiet show with no live studio audience due to the virus.
Dr. Anthony Fauci offered simple advice to elderly or vulnerably ill Americans in the wake of the outbreak.
Authorities are scrambling to track the other passengers who were cleared for travel and allowed to disembark the MS Westerdam cruise ship after showing no signs of illness.
A Holland America Line cruise ship has been unable to dock for almost two weeks, despite having no reported cases of the virus.
Royal Caribbean announced that anyone holding a passport from China, Hong Kong or Macau would be unable to board any of its ships throughout February.
The ship will remain in quarantine for at least another two weeks, as required by the Japanese government.
Around 6,000 passengers aboard the Costa Smeralda have been locked down in the Italian port of Civitavecchia.
The incident allegedly took place on a cruise vessel headed for the U.S. Virgin Islands.
"Oh my god, it was just emotion... I was so grateful," one of the stranded yachtsmen said, describing the moment he saw the rescue vessel.
A mysterious "Jamaican businessman" has been blamed by a British couple who are accused of smuggling cocaine, according to U.K. reports.
The Coast Guard closed Florida ports as the storm approached the East Coast, forcing several cruise ships to change their itineraries.
The unnamed Australian man was found in the water and taken back to the ship during a cruise in the Caribbean.
Fuwad Twalib Nassir, 29—a Kenyan national from Mombasa—had just started a new job aboard the Carnival Liberty in Port Canaveral, Florida.
The ring sent teams on two cruise ships traveling from South America to Australia, each carrying large amounts of cocaine.
Small boats in the bay rushed to the aid of those aboard the aircraft, which came in to land close to the city of Ketchikan.
"I told my husband, 'This is not the way we're supposed to be docking,'" one passenger said.
The jury held Royal Caribbean 70 percent responsible for the passenger's death.
The collision was captured on camera by alarmed onlookers.