The 60-year-old victim was taken to a nearby hospital following the crocodile attack in Northern Territory, Australia.
"The guest almost certainly did not contract COVID on our ship," the cruise line said in a statement regarding a passenger who died from COVID complications.
Florida Governor Ron DeSantis signed a bill into law in May that prohibited businesses operating in the state from requiring proof of COVID vaccination.
Tens of thousands of people in California reportedly were vaccinated at a site where only photocopies of vaccine cards were handed out.
"It's scary what is happening in Florida," Norwegian's attorney, Derek Shaffer, said. "All we're doing is trying to protect our staff and passengers."
The first U.S. cruise in 15 months sets off Saturday as the industry hopes to make a comeback. Florida law blocked the ship from requiring proof of vaccination.
"Guests eligible but not fully vaccinated or able to show proof of vaccination will be subject to testing and additional health protocols at their own expense," the company said. "Children not eligible for vaccines will be subject to complimentary testing and health protocols."
The maiden cruise of Odyssey of the Seas, the line's newest vessel, has been pushed back to July 31 "out of an abundance of caution."
While travelers will have a difficult time finding cruise ship voyages departing from the U.S, they can find trips in other regions of the world.
Norwegian Cruise Line CEO Frank Del Rio said the path to resuming U.S. cruises is "a bit rockier and a bit steeper" than expected, and he said a mid-summer restart "could be in jeopardy."
All volunteers must be at least 18 years old and be either fully vaccinated or provide documentation that they are not at high risk of severe COVID-19 illness.
The state has seen a loss of 49,500 jobs since the cruise industry came to a halt, with more than 6,000 former cruise workers having filed for unemployment.
It is the latest cruise operator to cancel voyages from U.S. waters as the industry calls on the CDC to
In addition to its U.S. sailings through June, the cruise line also canceled its European cruises through September 18.
The CDC currently advises Americans to avoid cruise travel because "the risk of COVID-19 on cruise ships is very high."
COVID-19 vaccinations will be required on the upcoming sailings from the Bahamas and St. Maarten, the company said.
"This is a highly uncertain area right now for ships calling at U.S. ports," travel medicine expert David Freedman told Newsweek.
The crew members who tested positive were reported to be "doing well, with only mild symptoms," according to the ferry company.
The SeaDream Yacht Club vessel, which had 37 Americans aboard, returned to Barbados on Wednesday after the passenger tested positive.
The cruise began in Heraklion, the capital of the Greek island of Crete, and was due to sail to Piraeus, near Athens.
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While Carnival Corporation confirmed it will "fully cooperate" with the investigation, Carnival Cruise Line announced it will resume voyages on eight ships from Miami, Port Canaveral and Galveston.
The cruise line has seen two of its ships report several confirmed cases of the COVID-19 virus since February.
Several major cruise lines—Royal Caribbean, Carnival, Celebrity Cruises and Crystal Cruises—have announced cancellations or changes to their itineraries for cruises in March and April.
More than half of those reported infected outside China were aboard the Diamond Princess cruise ship, which has been quarantined in Japan for over two weeks.
Authorities are scrambling to track the other passengers who were cleared for travel and allowed to disembark the MS Westerdam cruise ship after showing no signs of illness.
A Holland America Line cruise ship has been unable to dock for almost two weeks, despite having no reported cases of the virus.
Kenneth Ray Manzanares had been traveling with his wife and two children.