Brussels must expand the political inclusion of its member states in Central and Eastern Europe.
"The dysfunction of the EU is no longer sustainable," the French presidential frontrunner said.
Earlier this year, Le Pen repeatedly said that, if elected, she would seek a radical loosening of the EU's structure and, within six months, call a referendum on the outcome recommending a 'Frexit' divorce.
Bruno Le Maire would hold plebiscite by 2022.
Research finds demand for U.K.-style membership votes in other EU countries.
The Front National leader made the pledge during an interview with a Greek TV channel.