The space agency investigates new ways to grow plants in space to offer astronauts an alternative to processed food during long missions.
They're the first astronauts to launch to the station since the October mission that ended in an emergency crash landing.
SpaceX has been awarded a $2.6 billion contract by NASA to fly astronauts to the International Space Station.
The rocket will launch from the Wallops Flight Facility (WFF), on the eastern shore of Virginia.
The crew is completing a 197-day mission.
Dmitry Rogozin, the head of Roscosmos Federal Space Agency, said the SpaceX founder had deliberately undercut rocket launch prices "to squeeze Russia out of this market."
The matter will be cooled to just above absolute zero, or minus 459.67 degrees Fahrenheit.
Astronauts Drew Feustel and Rocky Arnold will spend more than six hours outside of the ISS Wednesday.
Astronauts on the International Space Station do not even have sinks because of the way water behaves in microgravity.
The company hopes it will be able to accommodate space-tourists by 2022.
Sperm was among the hundreds of things SpaceX sent to the International Space Station.
The space agency offered no explanation for why she was replaced.
Three more astronauts have arrived at the International Space Station.