Ayatollah Ali Khamenei suggested Washington does not want his regime's "religious democracy" to succeed.
"Instead of caving, Iran is moving step by step out of the nuclear deal and in recent months it hit six ships, attacked Saudi oil facilities and set fire to the U.S. embassy in Baghdad," Chris Wallace pointed out.
Both the U.S. and Iran have said they will no longer adhere to the Obama-era Joint Comprehensive Plan of Action.
The Hawaii congresswoman and Democratic presidential candidate said Trump is "putting all Americans in greater danger."
Johnson's comments to Iran's president came after Trump urged European allies, as well as Russia and China, to withdraw from the 2015 treaty.
"This moment right now is on Barack Obama, not Donald Trump," Fox News contributor Pete Hegseth said.
"I hate this," Rand Paul said, arguing that the situation with Iran was much better under the nuclear deal.
The Obama administration sanctioned Soleimani in 2011 over his involvement in a plan to assassinate a Saudi diplomat in Washington, D.C.
Robert Malley argued that Trump's policies towards Iran have put Americans "more at risk than they were before" he came into office.
Retired U.S. Ambassador John Limbert warned that President Trump had "no plan" and this could lead to a "disaster."
"In the world of politics, all things affect each other," Iran's foreign ministry spokesperson said Sunday.
An Iranian government spokesperson blamed the "bullying policy" of the U.S. and the "lack of resistance" by the Europeans,
The "maximum pressure" strategy's only effect was to make life miserable for Iran's civilian population, to prevent diplomacy and encourage U.S. allies like Saudi Arabia to act with greater bellicosity.
The energy secretary said Iran "could pay a very dear price economically" but added that Trump is "not interested in going to war."
Hamad bin Jassim bin Jabor al-Thani said Iranians won't crack under American economic pressure, and will look to play the long game instead.
Russian foreign minister Sergey Lavrov said American pressure on the Iran nuclear deal is designed to create a pretense for conflict.
Foreign Minister Javad Zarif gave an interview in New York City, where he is under tight visa restrictions, during a visit to the United Nations.
President Donald Trump said Sunday Iran had "better be careful" with its expansion of enriched uranium production.
"That's a very serious issue if they continue to do that," Trump's national security adviser warned.
"We are actually considering escalating with Iran in a war that would further destabilize the region and unleash God knows what in terms of chaos in a very troubled region already," Elise Jordan said.
War could become a fait accompli if Trump keeps Bolton in the White House.
Washington has been at odds with Europe over Iran since the Trump administration abandoned the 2015 nuclear deal.
"War with Iran is playing with fire, and it will burn all, and not just Iran," said Iranian lawmaker Alaeddin Boroujerdi.
"They have all shown an interest in dragging the United States into a conflict," Javad Zarif told Fox News Sunday. "I do not believe that President Trump wants to do that. I believe that President Trump ran on a campaign promise of not bringing the United States into another war."
Iran's General Amir Hatami said President Donald Trump's policies have promoted "such traits as selfishness, cruelty and violation of humanitarian principles and international rules."
The 2020 Democrats have to bring back the deal.
The president "rejoices over the misery that he thinks he has imposed on ordinary Iranians," Iranian Foreign Minister Javad Zarif wrote on Twitter.
"No one can defeat a nation which pursues resistance," Iranian President Hassan Rouhani said in a televised address, claiming the U.S. and its allies were to blame for the country's poor economy.
Ayatollah Ahmad Khatami pointed out that nuclear bombs are "clearly" against Islamic (or Sharia) law.