The Council on American-Islamic Relations said Biden "literally aids, abets and justifies the Israeli apartheid government's indiscriminate bombing."
Video of the moment has been shared widely on social media.
The Democratic congresswoman said violence and oppression of Palestinians has been "enabled and supported" by Israel's prime minister.
Palestinians are now certain they will be rewarded, not punished, for their aggression.
Israel will "stop the anarchy and restore governance to the cities of Israel, with an iron fist if needed, with all forces needed and all authorities required," Israeli Prime Minister Benjamin Netanyahu said on Wednesday.
Violence in Israel, the worst seen since the 2014 Gaza war, has left at least 36 people dead—five Israelis and 31 Palestinians.
"What we have witnessed is, clearly and frankly, a provocation by the Israeli occupation, that targeted the holiest Islamic sanctities, at the most sacred time," Ahmed Aboul Gheit, the head of the Arab League, told the Associated Press.
The New York mayoral candidate said he is "standing with Israel" amid reports nine children were killed in Gaza during airstrikes.
The recent escalation has been fuelled over claims over Jerusalem, which both sides see as their capital.
John Hagee, the Christian pastor famous for his passionate support of Israel, says elitists in government and the media are making a bad situation worse in Jerusalem.
Health officials reported a total of 20 deaths in Gaza, nine of which were children after an explosion. It is not known what exactly caused the blast.
The incident came during a particularly violent day after weeks of tension.
The United States has issued a condemnation of rocket attacks claimed by Hamas against Israeli cities and settlements, while Middle Eastern nations including Iran, Turkey and Arab states have condemned Israel's crackdown on Palestinian protesters and worshippers.
"We have serious concerns about the situation, including violent confrontations that we've seen over the last few days," White House press secretary Jen Psaki said on Monday, hours after Hamas militants fired rockets into Israel.
The clashes erupted as Israelis prepared to mark Jerusalem Day, celebrating Israel's annexation of East Jerusalem in 1967.
The incident took place near the Al-Aqsa mosque compound in east Jerusalem following days of mounting tension.
Most were injured after being hit in the face by rubber-coated bullets and shrapnel from stun grenades, the Palestinian Red Crescent said.
"Of course there are laws that some people may consider as favoring Jews—it's a Jewish state," Fleur Hassan-Nahoum, a deputy mayor of Jerusalem, said.
The two Palestinians were shot to death after they opened fire, along with another individual, on one of Israel's bases in the West Bank.
The message comes as several Palestinian families in the neighborhood continue to fight a long-standing legal battle with Israeli groups that are trying to acquire the property, as both sides view the land as their own territory.
Security forces in Jerusalem separately clashed with Palestinians angry about Ramadan restriction and Jewish extremists who held an anti-Arab march nearby on Thursday night.
Senators backed an amendment supporting the embassy move in a 97-3 vote on Thursday night.
The California Highway Patrol and Department of General Services have also installed a 6-foot chain link fence around the perimeter of the State Capitol in Sacramento.
By ignoring our three thousand-year link to the Temple Mount, the U.N. validates the Palestinian refusal to recognize our right to exist as the world's only Jewish state.
Secretary of State Mike Pompeo may have violated the Hatch Act when he pre-recorded his remarks for Tuesday's Republican National Convention while on a diplomatic trip to the Middle East.
Recep Tayyip Erdogan is an Islamist dictator with neo-Ottoman regional ambitions.
Bloomberg, who received a standing ovation when introduced at AIPAC, demanded bipartisan support for Israel from Democrats but never directly criticized Republicans or President Donald Trump by name.
"This is a political ploy by both leaders to distract from their abuse of power," IfNotNow's Emily Mayer said, referring to Trump and Israel's Netanyahu.