"Ah yes, the Conservative Dem position," Representative Alexandria Ocasio-Cortez tweeted, referring to the West Virginia senator.
The U.S. risks default for the first time in history if Congress doesn't raise the debt ceiling by October 18.
"It's a real possibility," Biden told reporters outside the White House.
Manchin last week proposed a $1.5 trillion limit on the budget reconciliation bill.
The former House Speaker was discussing recent confrontations by activists, adding that "if we ever decide to respond in kind, they'll be gone."
Sen. Joe Manchin (D-W. Va.) has cautioned progressives that the Build Back Better Act will be "dead on arrival" if his demand to include a ban on federal abortion funding is not met.
Loomer, who spouts anti-Muslim rhetoric, has praised the West Virginia and Arizona senators' resistance to the spending package.
The Arizona senator has taken flack from progressives, has protesters at fundraising events and now she's getting lampooned on Saturday Night Live.
"Mr. Richmond, I've got to...stop you there," said Wallace. "It doesn't cost zero. Whether it's $3.5 trillion or $2 trillion...it costs that amount of money."
"As a wine-drinking bisexual triathlete, I know what the average American wants," Cecily Strong said while playing the Arizona senator.
"We cannot let this small faction on the far left ... destroy the President's agenda," said Representative Josh Gottheimer.
"We can bring the moderates and progressives together very easily if we had two more votes. Two," the president said.
Ex-director of the National Economic Council, Larry Kudlow, told Fox News "at least somebody is stepping in front of this train."
"It doesn't matter whether it's in six minutes, six days, or six weeks," the president said. "We're going to get it done."
The Vermont senator tweeted, "2 senators cannot be allowed to defeat what 48 senators and 210 House members want."
The moderate West Virginia lawmaker says he would support a spending package totaling $1.5 trillion, versus the current $3.5 trillion price tag.
Some Democrats say they are not ready to fast-track a $1.2 trillion infrastructure package that would upgrade roads, bridges and broadband.
The West Virginia Democrat answered questions about the infrastructure bill he is holding out against.
Pelosi was confident this week they had the votes to pass an infrastructure bill, but it got delayed Thursday night as a battle within the Democrat Party churns.
"We need to get these bills done for the president, for his agenda, but also more importantly for the country," moderate Democratic Rep. Josh Gottheimer said.
Lawrence O'Donnell took aim at the Arizona senator for not explaining why she was holding up the Democrats' infrastructure package.
The West Virginia senator has said he can't support a proposed $3.5 trillion infrastructure package.
Senator might have shot down Democrats' hopes of passing this week a $1.2 trillion infrastructure package that's a main part of President Joe Biden's agenda.
White House aides noted that Democratic Senators Kyrsten Sinema and Joe Manchin do not usually respond to national political pressure.
The way to address climate change is with policies "that spur innovation not elimination," the West Virginia senator said.
Earlier this month, the senator penned an op-ed explaining why he would not support the Democrats' spending bill.
The moderate Senate Democrat said Congress needs to watch inflation to determine whether it is "transitory or not."
Biden told reporters Thursday that he's "confident" Congress will pass both the bipartisan physical infrastructure plan and the Build Back Better plan.