The list includes a former deputy national security adviser, Vice President Mike Pence's security aide and a hostage negotiator.
Scaramucci has turned his very short tenure with the Trump administration into a profitable position for himself.
"We have a president who seems to not want to hear anything other than 'yes,'" Susan Rice told MSNBC.
"It's perhaps not the best way to find your next cabinet," Alisyn Camerota, who previously worked for Fox News, said.
The Daily Show host mocked the departure of the national security adviser, who disputes that he was fired, insisting instead that he quit the Donald Trump administration.
Trump announced Bolton's departure on Twitter on Tuesday, saying he had disagreed with "many" of his adviser's suggestions.
"Why are they doing it?" Harris Faulkner said. "Why are we seeing this play one against the other almost in terms of, you know, what the narrative is?"
"I offered to resign last night and President Trump said, 'Let's talk about it tomorrow,'" Bolton tweeted 12 minutes after Trump published a tweet implying the National Security Adviser was fired.
The president may already be tiring of a maximum pressure policy that has resulted in much less than its supporters predicted.
Russia has backed Venezuelan President Nicolás Maduro against U.S. attempts to oust the socialist leader.
To Iran's top diplomat, national security adviser John Bolton is part of a "B-Team" pushing for war and, to Venezuela's leading general, his tweets are signs of an "obsessive-compulsive disorder."
The people never held to account for their warmongering in Iraq are now driving U.S. policy against Iran. They can't be allowed to drag us into another war.
Nearly all of the Iranian economy is now sanctioned, with little real effect. It's time for statesmanship and prudence, not chest-puffing and bellicosity.
President Trump sounds as if he is searching for a way out of the trap that the hawks in his administration have set for him. Will he make it out in time?
"Wars start sometimes or often by miscalculations and misunderstandings. This is a situation that's ripe for that," Senator Angus King cautioned.
"This is a very dangerous situation that we're in right now," Ryan said in an interview on Saturday.
"I think it's incredibly dangerous," Representative Seth Moulton warned.
"That's a very serious issue if they continue to do that," Trump's national security adviser warned.
National security adviser John Bolton, Japanese Prime Minister Abe Shinzo and now the State Department have all contradicted the president.
The president's national security adviser also suggested Iran is still seeking a nuclear arsenal despite its adherence to the 2015 nuclear deal.
"If he's working towards a deal, as you say, it's a deal we don't know about," John Brennan said. "He basically said he wants denuclearization. That is not going to happen."
Buttigieg argued that "it wouldn't be the first time" that Trump has "lost control of an international dynamic."
The North Korean official referred to Bolton as more of a "security-destroying adviser" than a security adviser.
Harsh words follow Bolton's criticism of Pyongyang missile tests.
Last week, North Korea's official Korean Central News Agency published commentary blasting Biden as a "snob lacking even the most basic qualities of a human being, much less a politician."
"Iran is no threat to anybody in Iraq or elsewhere, and Iran is not preparing for any attacks anywhere," the spokesperson for Iran's mission to the United Nations said.
President Donald Trump is angry that military planning has seemed to outpace his diplomatic efforts, according to a new report.
The plans are separated into two categories and involve airstrikes, targeted incursions and setting U.S. forces up for a ground invasion.
"We are actually considering escalating with Iran in a war that would further destabilize the region and unleash God knows what in terms of chaos in a very troubled region already," Elise Jordan said.