The administration understands Bashar al-Assad's utter subordination to Iran for the sake of Hezbollah.
The pontiff expressed sadness over deaths and said the U.S.-led coalition had an obligation to protect civilians.
Stephen Townsend said increases in civilians casualties are to be expected.
An Amnesty report cites two airstrikes in Mosul, which allegedly killed up to 300 people.
At least four prisoners have died, Human Rights Watch claims, in cases apparently linked to lack of proper medical care.
Forces recaptured the city's government complex as part of a new drive into western Mosul.
The key road links the northern Iraqi city to Syria.
The shrine was a reported burial site of a prophet known in the Koran as Yunus and in the Bible as Jonah.
A coalition of Iraqi forces is continuing its fight to oust the group from the northern city.
Searches are underway to establish the whereabouts of the troops.
Civilians escaping from ISIS-held territory in northern Iraq find that justice is not always forthcoming.
Iranian-backed Shi'ite paramilitaries have linked with Kurdish forces west of the city.
The attacks included 19 uses of hazardous materials on the battlefield around Mosul.
The numbers of those fleeing has increased as Iraqi forces edge further into the city.
Human Rights Watch has cited witness accounts of the prisoner massacre.
Iraqi authorities must take new measures to ensure thousands of vulnerable families are cared for.
Men dressed as Iraqi police allegedly carried out revenge attacks against civilians, rights group says.
Number 1: How did Erdoğan, born into poverty, become a billionaire?
The Turks have sent forces into Iraq without consent from the Iraqi government.
The elite unit had paused its advance to allow other units to make similar progress.
The Hashd al-Shaabi umbrella group has so far played a limited role in retaking Mosul.
Aid groups have warned of a humanitarian crisis in the fallout from the campaign.