Barcelona looks to remain top of the table when it travels to Madrid, while Atletico will be looking for its first league win against the Catalans in nine years.
Zinedine Zidane's team has won three of the last four league games and would go top of the table—at least until Sunday—with a win over Alaves.
The Welshman celebrated his country's qualification for Euro 2020 with a flag reading "Wales. Golf. Madrid. In that order."
The Blaugrana could momentarily open a three-point lead over Real Madrid when they take on Leganes on the road in the early kick-off on Saturday.
The Catalans are on a two-game winless streak in all competitions and their coach is under severe pressure.
Real has won three of the last four games, scoring 12 goals without conceding, and looks to keep the run going away at Eibar.
Los Blancos look to make it three consecutive wins in all competitions when they host Real Betis on Saturday.
The Blaugrana look for a sixth consecutive win in La Liga when they travel to Valencia on Saturday afternoon.
Real Madrid returns to action in La Liga on Wednesday when it hosts bottom-of-the-table Leganes, looking for a first league win in three weeks.
After an unexpected weekend off because of El Clasico's postponement, Barcelona can go back to the top of La Liga when it plays Valladolid on Tuesday.
The league leaders travel to Mallorca looking to retain their unbeaten start to the campaign and hoping to consolidate top spot.
Barcelona looks to make it four wins in a row when it takes on Eibar on Saturday but the focus will likely be on pro-Catalonia protests.
Barcelona is scheduled to host Real Madrid on October 26 but La Liga is reportedly worried about clashes following the arrest of nine Catalan leaders.
Barcelona looks to extend its winning run to three games, while Sevilla searches for a first win at the Camp Nou since 2002.
Madrid hosts Granada in a top-of-the-table team on Saturday with Los Blancos looking to maintain their unbeaten record.
League leaders Sevilla hosts Real Madrid on Sunday, with Zinedine Zidane's team looking to rebound from a 3-0 loss against PSG.
Lionel Messi could make his first start this season when Barcelona travels to Granada on Saturday looking for a second consecutive win.
Barcelona looks to shake off a difficult start to the season when it takes on Valencia this Saturday afternoon.
Eden Hazard is set to make his Real Madrid debut as the 13-time European Cup winners host Levante on Saturday.
Real Madrid looks for a second consecutive away win when it takes on Villarreal on Sunday—and it could have Eden Hazard back.
The defending La Liga champions look for a second consecutive win against Osasuna in Pamplona on Saturday.
The defending La Liga champions look to get their campaign back on track after losing to Athletic Bilbao in the first game of the season.
The 13-time European Cup winners make their home debut this season looking for two wins in two La Liga games.
After a big overhaul in the summer, Real Madrid begins its league campaign against Celta Vigo on Saturday.
After a summer of lavish spending, Barcelona begins its quest for a third consecutive La Liga title on Friday.
Defending champions Barcelona get the ball rolling on Friday when they take on Athletic Bilbao.
The Spanish champions are already planning for next season.
"Now, 100 million euros is nothing. It was a lot when I paid for Cristiano Ronaldo."
Ernesto Valverde's team is marching toward the title in his first season in charge at the Nou Camp.