The late-night host weighed in on the end of Donald Trump's second impeachment trial on Tuesday night, with special attention given to the Senate minority leader.
After the broadcaster's 2013 interview with Lindsy Lohan went viral this week, we look back at other tense interviews David Letterman had with Janet Jackson, Cher, Paris Hilton and more.
"So tonight, no Britney Spears jokes. This woman has two kids, she's 25 years old, she's a baby herself," Ferguson said on a 2007 episode of The Late Late Show.
"I mean, how dare you salaciously gossip about this woman after she 'Be Best' for you!'" Meyers joked on Monday's installment of "Late Night with Seth Meyers."
"So maybe save that dose for someone else," Kimmel said Thursday night in a scathing rant about the vice president.
"Remember how everyone made fun of Hillary Clinton for taking a walk in the woods once after she lost? Trump's going to have to live in the woods," Meyers said.
Stephen Colbert has brutally mocked President Donald Trump, comparing the president's legal losses to the first lady rejecting holding his hand.
The late-night host lambasted Donald Trump's lawyer, mocking her for not wearing a mask before contracting COVID-19, and for attending a Christmas party at the White House
"I mean, this dude was going all over the country refusing to wear a mask. What do you expect?" The Daily Show host said on Monday's episode.
The former president also spoke about Joe Biden's victory during his appearance on "The Late Show" Tuesday night, expressing hope for the next four years despite the challenges that lay ahead.
Members Jisoo, Jennie, Rosé, and Lisa will be unveiling their new single "How You Like That" on the show.
"You made the classic zombie-movie mistake. When you are in the house, and someone knocks on the door, you don't let that person in. It's going to be a zombie – or a Jehovah's Witness," Noah said during Wednesday's episode of "The Daily Show."
"Defunding the police absolutely does not mean that we eliminate all cops and just succumb to the purge," John Oliver explained Sunday on "Last Week Tonight."
"When a man like Donald Trump uses the word 'thugs', you know exactly what it's code for," John Oliver said on "Last Week Tonight" on Sunday.
"I don't want to jinx myself, but I'll tell you why: The American people, they fully understand what's at stake here," the former Vice President said during an appearance on "The Late Show with Stephen Colbert" on Thursday.
'The Masked Singer' judge showed off the newest member of his family, a Golden Doodle named Mocha, while chatting with James Corden on Wednesday night.
"Fred was always funny," Kimmel said during his Monday show. "He was more than funny. He had a light inside of him."
"Dr. Tan-hattann, of course, was watching Dr. Bright on TV and he stopped on the lawn this morning to yell about him," Jimmy Kimmel said during his latest show.
"I guess it just comes down to who you believe: the doctor, who's one of the world's leading experts on infectious disease, or our personal pan president," Jimmy Kimmel said on Tuesday.
"I would like the vice president—since he asked me to apologize—to ask his boss, who lies every time there isn't a McNugget in his mouth, to apologize for the following perversions of decency and democracy," Jimmy Kimmel said.
"This is not a Democratic or Republican issue. The virus does not discriminate. You have Democrats dying, you have Republicans dying. It's not a red-state, blue-state issue," New York Governor Andrew Cuomo said on 'The Late Show With Stephen Colbert' Thursday.
Stephen Colbert thought Governor Andrew Cuomo's hot take on the value of human life was a "refreshing contrast" to President Donald Trump's position.
"How about liberating the scientists, letting the CDC hold a press conference of their own every day or the National Institute of Health?" CNN's Anderson Cooper said during his appearance on "The Late Show" on Monday night.
"Obviously we wish we could've announced it on our own terms, but we're very excited and happy and grateful for everyone's well wishes and support," Gigi Hadid told Jimmy Fallon during her appearance on 'The Tonight Show' Thursday.
"He didn't want to wear a mask because he wanted to look them in the eye and say thank you. What kind of mask was he planning to wear? Spider-Man?" Kimmel asked on his late-night show.
"He'd be yelling at some reporter and saying, 'This is why I know about the aliens and you don't!'" Kimmel said during his quarantined monologue on "Jimmy Kimmel Live" on Tuesday.
"Dr. Donald Jingleheimer Trump spent the weekend trying to pretend he wasn't really suggesting we should inject disinfectants into our bodies. He claimed he was being sarcastic," Jimmy Kimmel said on his late-night show on Monday.
"We're in the middle of a pandemic and Trump's people are scrambling like they're on an Andy Cohen reunion show," Trevor Noah said on "The Daily Show" on Thursday night.