Argentina was eliminated by Brazil in controversial fashion, while Chile's bid for a third consecutive title came to an end against Peru.
Brazil and Argentina renew their rivalry in the semifinals, while Chile takes on Peru hoping to reach the final for the third time in a row.
Brazil and Argentina square off on Tuesday night for a place in the final, while Chile plays Peru on Wednesday.
Brazil takes on Paraguay in the quarter-finals, while Argentina faces Venezuela and the two rivals could meet in the semi-finals.
Brazil is a heavy favorite against Paraguay, while Argentina faces a tricky test against Venezuela on Friday.
Argentina vs Colombia is the first heavyweight clash of the tournament, while Chile vs Uruguay could be crucial.
The 46th edition of the tournament gets underway on Friday and promises to be one of the most even in years.
Brazil hosts the Copa America this year but has not won the tournament in 12 years and will be without Neymar.
"In the Argentina against Iceland game we saw just how much Messi needed the warm-up game against Israel."
The 411 on this summer's biggest sporting event.
The campaign will see 10,000 school meals donated each time Neymar or Messi score at this World Cup.
Ernesto Valverde's team is marching toward the title in his first season in charge at the Nou Camp.
In seven meetings in La Liga, Barcelona has beaten Eibar each time and scored 26 goals.
Ernesto Valverde's team already has an 11-point lead on Real heading into the game.
He is believed to have played a crucial role in Romelu Lukaku's move to Old Trafford.
The Brazilian only just left the club, joining Paris Saint Germain for £199 million in the summer.
Kane showed his quality in Spain on Tuesday during Tottenham's 1-1 draw with Madrid.
The world transfer record was broken this summer, when PSG paid £199 million for Neymar.
The Spanish giant has a history of plucking English football's best with large fees.
The Belgian is the subject of interest from the Spanish giant.