District Judge Kiyo Matsumoto said the 37-year-old's "self-described altruistic intentions" do not not provide a legal basis to grant an early release.
Shkreli, who became infamous for dramatically hiking the price of a life-saving drug, is currently serving a seven-year prison sentence for a securities fraud conviction.
Shkreli will do whatever it takes to win. His kind can be found on Wall Street, in Hollywood, in Silicon Valley, and in Washington.
The "Pharma Bro" will also have to forfeit a supposed Lil Wayne album and a Picasso.
A surreal ending for the saga of the most expensive record ever sold.
The former CEO used his Facebook page to make the call for the hair.
The former pharmaceutical company executive has criticised prosecutors, witnesses and media during his ongoing securities fraud trial.
Potential jurors labeled the former drugs company chief who hiked prices for an AIDS drugs 5,000 percent "the face of corporate greed" and "the most hated man in America."
The White House blocks The New York Times, CNN and Politico but lets in Breitbart.
The ex-pharmaceutical exec has a habit of spending millions to keep albums all to himself.
An artist said he never allowed his fan art depicting Wu-Tang members to be used in packaging for the hip-hop group's "Once Upon a Time in Shaolin."
Shkreli, 32, sparked outrage last year after Turing raised the price of 62-year-old Daraprim to $750 a pill from $13.50.
It's surprisingly easy to hoax reporters with a viral tweet.
Clinton's criticism sent drug industry stock prices tumbling.
Shkreli's drug company raised the cost of the anti-infective drug to $750 from $13.50 per pill recently.