"These disruptions...are going to continue for a while," Mississippi State Epidemiologist Dr. Paul Byers said.
One state senator said he was compelled to get a vaccine due to rising cases.
"I think traditionally people kind of considered, 'Well, you know, kids aren't going to get that sick with this…' That's not the evidence."
"I didn't make this decision without extensive consideration of all factors but I am convinced this action is the best path forward given the ever-changing environment we currently face," Governor Tate Reeves wrote.
Doctors expressed concerns about having enough staff to care for patients in addition to needing space for them.
The state has the lowest number of vaccines administered per 100,000 people out of all U.S. states—but this figure is increasing fast.
"It's pretty amazing and great motivation for our fans and the state," Kiffin told ESPN while speaking about the team's 100 percent vaccination rate.
The Mississippi Department of Health reported 2,094 cases of COVID-19 on Friday and eight COVID-related deaths.
Tyler Kuntz, who teaches music in Oxford, Mississippi, said he opposed the decision to bring back a mask mandates without asking for parents' input.
Officials said they are feeling "some low level of anger" at those still not getting vaccine as hospitals near breaking point.
The state saw nearly 5,000 new cases over the weekend, according to state data, more than six times the confirmed amount reported on July 12.
Governor Reeves said the new mask guidance "has nothing to do with rational science."
Louisiana, Mississippi, Oklahoma, Alaska, South Carolina and Florida have all seen a significant rise in new cases in the past week.
Till, a 14-year-old Chicago resident, was murdered by white supremacists 66 years ago while visiting his great aunt and uncle in the rural Mississippi Delta.
The brief asks the U.S. Supreme Court to overturn the landmark decision to legalize abortion and allow states to decide how to regulate the practice.
Health officials have reported ICU units at 13 hospitals in the state are now full, and have urged people to get vaccinated.
Florida has seen a fivefold increase, while Alaska's average has gone up fourfold and Mississippi's has tripled. Arkansas has also seen a spike in cases.
Seven children battling COVID-19 in Mississippi were receiving treatment in ICUs on July 13, with two of those children on life support.
Ten of 12 children who were in intensive care units in Mississippi Tuesday for treatment of COVID-19 were on life support, the state's top health official said.
"I am deeply troubled that some of our student-athlete parents were subjected to racist slurs during last night's game," Candice Storey Lee tweeted Tuesday.
After traveling through the Carolinas on Monday morning, Tropical Storm Claudette is expected to head out to the Atlantic Ocean and travel to Nova Scotia on Tuesday.
Heavy rain in Mississippi breached levees and dams, flooding roads and farmlands, and left some residents able to access their homes only by boat.
Stark state-to-state variation in vaccine rates had prompted the White House to implore governors to increase their numbers, particularly in Mississippi, where only 34 percent of the population has received their shots.
A juvenile has been arrested in connection to the murder, and a second suspect is still on the run, authorities said.
Ashton Walden died in hospital after his 2-year-old sister found a gun under a car seat and accidentally shot him.
Social media users criticized a photo showing officers surrounding Eric Boykin after his arrest in Prentiss, Mississippi.
Shortly after the yearbook was sent home with students, numerous parents posted pictures of the prompts and criticized the school for allowing them to be included.
While the charming duo offered some unique challenges to the rescue team, they were recovered from the drain safe and sound.
A nominally conservative Court is set to decide the fate of the legal conservative movement itself.
A huge and stubborn alligator gave local authorities a run for their money on Tuesday when it refused to move from its spot in front of a Mississippi home.