Georgia returns to the Sugar Bowl a year after losing to Texas, while Baylor could clinch a first 12-win season.
The Pac-12 champions and the Big Ten runner-up collide in the Rose Bowl for the first time since 2012, both looking to end the season on a high.
No. 9 Florida can end the season with 11 wins for the first time since 2012 if it defeats No. 24 Virginia on Monday.
No. 2 ranked Ohio State and No. 3 ranked Clemson meet in the CFP semifinal for the first time since 2016.
The No. 1 Tigers meet the No. 4 Sooners in Atlanta with both teams looking for a first ever appearance in the CFP national title game.
Memphis makes its first appearance in a New Year's Six bowl, while Penn State plays in its third in four years.
College football's New Year's Six bowl games get underway on December 28 with the Cotton Bowl and the two College Football Playoff semifinals.
The college football bowl season gets underway on Friday, with the two CFP semifinals scheduled for December 28.
LSU's Joe Burrow is the overwhelming favorite to become the fourth consecutive quarterback to win the prestigious award.
The 120th instalment of the rivalry between Army and Navy takes place in Philadelphia on Saturday, with the Midshipmen looking to snap a three-game losing streak against their rivals.
On Sunday the College Football Playoff selection committee will determine the four teams that will compete for the national title.
The Buckeyes can clinch a third consecutive Big Ten Championship with a win over Wisconsin in Indianapolis on Saturday.
The Tigers can become the first team in FBS history to win five consecutive conference championship games with a victory over the Cavaliers on Saturday.
The second-best offense in the nation goes up against the No. 2-ranked defense in the country on Saturday when the Tigers face the Bulldogs in Atlanta.
Two weeks after Oklahoma won a 34-31 shootout on the road against Baylor, the two conference rivals meet again with a Big 12 title on the line.
Clemson is the biggest-favorite of any of the FBS teams in action in a conference championship game this week.
Championship Week begins on Friday night, when Utah and Oregon collide for the Pac-12 title, with a further nine games scheduled for Saturday.
The top four is expected to remain unchanged going into Championship Week, but Alabama should fall down the rankings after losing to Auburn in the Iron Bowl.
No major changes are expected in the top four of the latest CFP rankings, but Alabama is set to fall away after losing to Auburn in the Iron Bowl.
Utah and Oregon kick off Championship Week when they meet in the Pac-12 title decider on Friday, with LSU facing Georgia in the SEC title game on Saturday.
The No. 7-ranked Sooners take on state rivals and No. 21-ranked Cowboys needing a win to keep their College Football Playoff hopes alive.
No. 2 ranked LSU can go 12-0 with a win over the Aggies and avenge last season's controversial loss after seven overtimes.
The Bulldogs can improve to 11-1 and extend their winning run over the Yellow Jackets to three games on Saturday.
No. 1 Ohio State travels to No. 13 Michigan on Saturday looking to extends its winning streak over the Wolverines to eight.
No. 5-ranked Crimson Tide must win on the road against the No. 15 Tigers to keep its hopes of a spot in the College Football Playoff alive.
The No. 3-ranked Tigers are 11-0 and could go unbeaten in the regular season for a second consecutive year.
No. 1 Ohio State faces No. 13 Michigan on the road, while No. 5 Alabama takes on No. 15 Auburn in the Iron Bowl and No. 7 Oklahoma faces No. 21 Oklahoma State,
Ohio State leapfrogged LSU at No. 1, while Clemson and Georgia rounded up the top four and Utah climbed up to No. 6.