The Steelers are 0-2 and lost their veteran quarterback for the season to an elbow injury on Sunday.
Both the Browns and the Jets will be desperate to avoid a second consecutive defeat when they meet at MetLife Stadium on Monday night.
The veteran quarterback was replaced in the first quarter with a thumb injury and will see a hand specialist in Los Angeles.
Week 3 of the regular season kicks off on Thursday night when the Jacksonville Jaguars host the Tennessee Titans.
The Eagles travel to Atlanta looking to make it back-to-back wins, while the Falcons must avoid a second consecutive loss.
The 11th overall pick of the 2018 NFL draft has grown frustrated with covering multiple positions and reportedly wants out of Miami.
The Bucs and Panthers kick off Week 2 of the NFL season, and both need a win after losing their opening games.
Troubled wide receiver was expected to make his debut for the Patriots in Week 2 after signing a one-year deal on Monday.
The Philadelphia Eagles, Seattle Seahawks and Minnesota Vikings are among the teams unveiling rooms for fans with autism, Down syndrome, PTSD or other conditions who need to get away from the roar of the game.
The Patriots travel to Miami in what could be a hopelessly lopsided game, while Cleveland must turn things around on Monday night on the road against the Jets.
The Steelers begin their defense of the NFC South title when they take on the Texans in New Orleans Monday night.
After an offseason dominated by Antonio Brown's shenanigans, the Raiders can finally concentrate on football when they host the Denver Broncos on Monday night.
An unnamed Cleveland Browns fan was captured on camera by 19 News' live broadcast as he fell off the top of a van on Sunday morning.
The Patriots begin their quest for a seventh Super Bowl ring when they host the Steelers in Foxborough on Sunday night.
Antonio Brown has made headlines all offseason, and not for anything he has done on a football field. It's what has happened off of it, especially within the last week.
The 100th NFL season gets underway on Thursday night as the Bears host the Packers at Soldier Field.
Focus on the Family founder James Dobson has argued gays and lesbians can be cured and find "wholeness in their newfound heterosexuality."
The traditional long-hour documentary celebrating the most recent Super Bowl winners premieres at 9 p.m. ET on Wednesday.
The running back has turned down the offer of a $10 million-a-year deal and the Chargers have told his representatives to seek a trade.
The Dallas Cowboys star is yet to sign an extension and his participation in Week 1 remains in doubt.
Patrick Mahomes could become the first player since Peyton Manning in 2009 to win back-to-back MVP awards.
The 100th NFL season gets underway on Thursday as the Chicago Bears host the Green Bay Packers at Soldier Field.