"Those who threaten to wipe us out, put themselves in a similar danger, and in any event will not achieve their goal," Netanyahu said from a nuclear facility on Wednesday.
The aid package, agreed to on Thursday, will support the public and private sector in a bid to save a plan known as the Iran Nuclear Deal.
The oil company cut ties with Iran to avoid new U.S. sanctions, the Iranian oil minister said on state television Monday.
Iranian President Hassan Rouhani and Foreign Minister Javad Zarif initially argued that the deal would bring a windfall of foreign investment, but that promise did not materialize.
United States Ambassador Robert "Woody" Johnson called on British leaders to join the U.S. in "turning up the pressure" on Iran, or face "serious consequences." Washington recently reimposed sanctions on Iran despite opposition from allies.
Despite Khamenei promising that war is not an option, he also said that dialogue with Washington is not on the table.
Prices could reach $90 a barrel.
"I am asking for WORLD PEACE, nothing less!" Trump said in early-morning tweet.
"Even in the worst case, I promise that the basic needs of Iranians will be provided. We have enough sugar, wheat and cooking oil. We have enough foreign currency to inject into the market," Rouhani said.
"Don't play with fire, or you will regret."
President Hassan Rouhani's chief of staff said the current Iranian administration and the Iranian people "will not yield to pressure."
The U.S. is legally "obliged to stop these international breaches and compensate for all the damage inflicted," Iran says.
Israel aims to influence the framework of any U.S.-Saudi nuclear deal to ensure its concerns are taken into account.
"We have not allowed, under any circumstances, [problems] to become justifications or excuses."
Macron responded to Rouhani by saying that he "hoped that Iran, for its part, will fulfill its obligations without any ambiguity."
"He is no longer immune. His regime is no longer immune," the Israeli leader said.
The Israeli Embassy in Washington, D.C., responded to Iranian Ayatollah Ali Khamenei on Twitter in a far more comedic tone after the supreme leader's comments that Israel is a "malignant cancerous tumor."
The trove of 100,000 files was snatched from a Tehran warehouse in January.
The EU's Federica Mogherini praised Beijing's efforts to save the deal.