The world No. 1 takes on Spain's Pablo Carreno Busta, while Medvedev plays Australia's Alexei Popyrin.
Williams faces China's Wang Qiang, while Federer takes on Australia's John Millman and Coco Gauff plays Naomi Osaka.
Williams faces Slovenia's Tamara Zidansek, while Federer takes on Serbia's Filip Krajinovic and Djokovic plays Japan's wild card Tatsuma Ito.
The first Grand Slam of the season begins in Melbourne on Monday, with some of the tournament favorites all in action.
The 108th edition of the Australian Open gets underway in Melbourne on Monday, with the women's and men's final scheduled for the first weekend of February.
Novak Djokovic and Serena Williams are the bookmakers' favorite to add an eighth Australian Open title to their collections this year.
The first Grand Slam tournament of 2020 gets underway on January 20 in Melbourne with Novak Djokovic and Naomi Osaka looking to defend their titles.
Roger Federer, Novak Djokovic, Rafael Nadal and Serena Williams are among the players in action in the fundraiser for the victims of the bushfires.
Environmental activists have called for Federer to cut ties with a company that has invested millions in fossil fuel.
The Spaniard is odds-on favorite to win a 19th Grand Slam title after Novak Djokovic and Roger Federer were both knocked out.
Federer chases a first semifinal at Flushing Meadows since 2015, while Williams looks to take another step towards a 24th Grand Slam title.
Federer takes on Britain's Dan Evans, while Djokovic faces American qualifier Denis Kudla on Friday evening.
Coco Gauff plays Hungary's Timea Babos, while Rafael Nadal takes on Australia's Thanasi Kokkinakis on Thursday.
The world No. 1 and the world No. 3 are both in action on Wednesday, as are the Williams sisters.
Rafael Nadal and Coco Gauff are both in action on Tuesday as the first round of the U.S. Open is completed.
The world number one takes on the number 23 seed as he looks for a second consecutive Wimbledon final.
Federer and Nadal will renew their rivalry on Centre Court on Friday, 11 years after they last met in an epic final.
Roger Federer and Rafael Nadal go head-to-head at Wimbledon for the first time in 11 years on Friday.
Men's tennis's Big Three have looked in imperious form so far and are all in action in the quarterfinals at Wimbledon on Wednesday.
Federer plays Italy's Matteo Berrettini, Nadal takes on Portugal's Joao Sousa and Djokovic faces France's Ugo Humbert.
Federer plays Britain's Jay Clarke in the second round, while Nadal takes on Nick Kyrgios in a potentially tricky encounter.
Roger Federer, Rafael Nadal and Serena Williams begin their campaign at Wimbledon on Tuesday morning.
The 133rd edition of the oldest Grand Slam tournament begins on Monday as Federer looks for a ninth Wimbledon crown.
The 133rd edition of the oldest Grand Slam tournament gets underway on Monday as Novak Djokovic and Angelique Kerber look to defend their titles.
The semifinals of both the men's and the women's tournament are scheduled for Friday, June 7 as Rafael Nadal and Roger Federer go head-to-head again.
The two rivals go head-to-head in the French Open semifinal on Friday and experts believe Nadal will have the better of his old foe again.
The world number two and number three are in action on Tuesday and could meet in the semifinal
Roger Federer aims to clinch a ninth Wimbledon crown while Serena Williams returns to action.
From soccer to tennis to basketball, it's clear that it pays to be gifted athletically.
The Swiss maestro, appearing in his 11th Wimbledon final, was challenged early on but once he broke a nervous Cilic in the fifth game of the opening set the match became a no-contest.