"If you're just flying under the radar, just trying to get your check...then what's the point of being in politics?" the New York Democrat said on Showtime's "Desus & Mero."
The show kicks off at 8 p.m. ET on ABC.
"The Conners" will continue to tackle topical issues like drug use, health care and making ends meet.
"There was a debt owed to this fictional family. We want to finish telling this story."
"It wasn't enough to [fire me], they had to so cruelly insult the people who loved that family and that show," Barr said.
John Goodman talked about Roseanne Barr's firing from the ABC show for racist tweets in an interview with a newspaper.
"I'm trying to talk about Iran!" Barr, 65, said. "I'm trying to talk about Valerie Jarrett [writing] the Iran deal!"
"Many of us have denounced what she said—which has nothing to do with our party, our movement, or our true beliefs," Lahren said of Barr's tweet.
"So full of racism, conspiracy theories and personal attacks. Abhorrent, bordering on presidential."
The manipulated photo showed John McCain's face atop the body of Virginia Tech Shooter Seung-Hui Cho, who killed 33 people at the university in 2007.
ABC isn't the only network with sitcoms about "tight-knit, working class" families.
"It was stone cold racist comment. It wasn't a joke, it was mean spirited, it was vile. ABC knew this about her going in," Steve Schmidt said of Roseanne.
ABC canceled Barr's sitcom shortly after she wrote the racist tweet.
Barr said she was going to leave Twitter after receiving criticism for her racist rant toward Valerie Jarrett on Tuesday, but it seems the comedian is still actively tweeting.