Mayfield is confident he will play against the Pittsburgh Steelers on Sunday, while Newton has been removed from the COVID-19 list.
Bell's disappointing stint with the New York Jets is over after just 17 games, so where could the running back land next?
The footage superimposed Trump's head over Aiyuk's body leaping over a player on Sunday during a spectacular 38-yard touchdown run.
A banged-up Philadelphia Eagles travel to San Francisco looking for their first win of the season, while the 49ers hope to improve their record to 3-1.
Despite six-figure penalties dished out to five head coaches and each of their teams, the NFL continues cracking down on those who don't follow its coronavirus protocols.
Their respective teams were also fined $250,000 each, bringing the total fines of not wearing masks to more than $1 million. That didn't include Monday night's games.
Players dropped like flies in Week 2 of the NFL season, with at least two stars suffering potentially season-ending injuries.
The former NFL quarterback accused the league of running "propaganda" proclaiming to care about Black lives while it simultaneously undermines fellow free agent Eric Reid for speaking out in support of the Black community.
The 49ers and the Seahawks look set to battle for divisional dominance, while a new era begins for the Rams.
Kaepernick's legacy is already going to be his work off the field in bringing awareness to social justice for black Americans, not his 11-24 record over his last three seasons as a starter. Would playing a backup role now diminish his work since 2016?
The six-time Super Bowl winner will become a free agent on March 18 and could leave New England after two decades.
Joyce Vance said Tuesday that the president's latest round of pardons are for political gain rather than any commitment to justice.
The Chiefs overcame a 20-10 deficit in the fourth quarter to win Super Bowl LIV, becoming only the fifth team in history to erase a double-digit gap in the Super Bowl
Kansas City is a 6/1 favorite to win Super Bowl LV and become the first team to win back-to-back Super Bowls since the Denver Broncos in 1999.
The Kansas City quarterback is the first player to appear on the Madden NFL cover, play in the Super Bowl and win the Lombardi Trophy in the same season.
Mahomes is the youngest player in history to win both the MVP and the Super Bowl and the third youngest Super Bowl MVP.
The Kansas City Chiefs won their first Super Bowl in 50 years with their come-from-behind victory over the 49ers. This is Kansas City's second Super Bowl win in history.
The early picks are in for NBC, ESPN, NFL Network and Sports Illustrated, and it's a mixed bag. The Fox picks were made about 45 minutes before kickoff, and they're now listed..
The NFL season culminates on Sunday, with the 49ers looking to win a sixth Super Bowl title, while the Chiefs search for their first Lombardi Trophy in 50 years.
Expect the San Francisco 49ers to run the ball, Patrick Mahomes to target Travis Kelce and can Andy Reid win his first ever Super Bowl?
The Kansas City Chiefs enter the NFL championship game as a 1.5-point favorite, while the 49ers are 28/25 underdogs.
From the length of the national anthem, to the color of Gatorade poured on the winning coach and Donald Trump's Twitter activity, there are hundreds of prop bets available.
Don't forget the dip! America pauses for its annual NFL ritual, with betting, cheering and guacamole—and this year, no Patriots.
Patrick Mahomes and Jimmy Garoppolo are the favorites to be named MVP on Sunday, with 49ers running back Raheem Mostert firmly in contention.
Super Bowl LIV will be just the fifth in NFL history to begin with a spread smaller than two points that began as favorites by three points or less are only 8-7.
The Chiefs make their first Super Bowl appearance in 50 years, while the 49ers return to the NFL's biggest game for the first time since 2013.
Unlike other sporting events, each Super Bowl is identified by a specific number as a bid to avoid confusion.
Super Bowl LIV will be the 11th played in the Miami area, more than any other city or region in the U.S.
The 49ers want to wear their throwback 1994 uniforms, which they've already worn twice this season.