The 49ers are off to their best start in almost three decades, while the Packers and the Saints look nailed-on to reach the playoffs.
On Monday night Nick Bosa, defensive end for the San Francisco's 49ers imitated Browns quarterback Baker Mayfield's celebration in college. The celebration occurred after the Oklahoma Sooners led by Mayfield beat the Ohio State Buckeyes where Bosa played.
San Francisco is 4-0 for the first time since 1990, when it won its first 10 straight games and went all the way to the NFC Championship Game.
The 49ers look to extend its perfect start of the season to 4-0, while the Browns aim to take sole control of the AFC North.
The 49ers hope to conclude preseason with a fourth consecutive win, while the Chargers are still looking for their first win.
The final round of NFL preseason sees all 32 franchises in action on Thursday night, just a week before the regular season gets underway.
The Denver Broncos have lost both of their preseason games and have been hampered by poor discipline, while the 49ers have already lost players to injuries.
The Cowboys gear up for Week 1 of preseason but have a number of contractual issues to sort out off the field.
NFL legend believes Brown "wants to come to San Francisco really bad" after WR dropped hints of wanting to leave Pittsburgh.
Three Giants fans filed a federal lawsuit claiming their constitutional rights were violated and excessive force was used when law enforcement officers ejected them from Levi's Stadium in San Francisco.
The former Alabama star was arrested on Saturday at 9 p.m. in Tampa Bay, Florida.
The 23-year-old threw for 262 yards and three touchdowns in his first NFL game.
Niners' general manager John Lynch revealed he asked the Patriots about Brady after having an offer for Jimmy Garoppolo rebuffed.
Jones said last week that Cowboys players will not be allowed to remain in the locker room during the anthem.
You believe in yourself," Garoppolo explained. "That's the best way to put it."
Sherman signed a three-year deal with the San Francisco 49ers on March 10.
'Sports Illustrated' released an excerpt on Tuesday.
Does this remind anyone of Colin Kaepernick's emergence in 2012?
Is this all part of the Bill Belichick master plan?
Does short rest guarantee clumsy football?
Kaepernick is without a team heading into the new NFL season. A "United We Stand" rally aims to change that.
The former San Francisco QB still doesn't have a job in the NFL.
The U.S. president took a jab at the quarterback's free agent status at a rally in Kentucky.