Wheeler took over from Scott Pruitt after Pruitt resigned following a string of scandals and misconduct allegations.
Rollbacks in air-quality regulations will cause a rise in heart disease, dementia and many other ills.
Pruitt, who resigned as EPA administrator amid a number of scandals, is succeeded by an energy industry lobbyist.
If the case proceeds as scheduled, the EPA will have to produce research to back Pruitt's claims about climate change.
The EPA secretary set up a call with the fast-food chain's top executive last year for a "business opportunity."
"There must be 60 hotels in Washington. I don't believe the mattresses in the Trump hotel are any better. This is just weird," Richard Painter said.
The Health and Human Services' study noted a certain class of toxic chemicals found in water supplies near military bases was dangerous at one-sixth the level previously thought.
Trumponomics is a thin veneer of an excuse for giving America's rich whatever they want, while sticking it to everyone else.
The new allegations come from a former staffer who worked on Donald Trump's 2016 presidential campaign.
The president said the agency chief's "bold actions" had led to the threats.
The EPA chief, who is facing ethics violation allegations, has reportedly been eyeing the role for months.
Pruitt has had a "consistent disregard for transparency from the time he was attorney general to his time as EPA administrator," the leader of a watchdog group said.
Powerful polluters want the Trump administration to make coal ash great again, and they are about to make it happen.
"As representatives of the American taxpayers, we are responsible for ensuring that their hard-earned money is not wasted."
The purchase is currently under investigation of the Government Accountability Office.
Lobbyists with the energy sector have pushed the EPA to scrap the Obama-era water rules for months.
The agency is gutting research focused on such products.
Meanwhile, EPA Admin Scott Pruitt racked up $90,000 in travel bills last June alone.
Scott Pruitt, head of the Environmental Protection Agency, cares much more about his next political office than he does about melting ice caps or ozone levels.
Advocacy groups have accused the Environmental Protection Agency administrator of "thwarting meaningful public participation."
New Jersey Senator Cory Booker asked EPA Admin Scott Pruitt about the proposal in a hearing on Tuesday.
The EPA has been posting signs with images of Trump and Scott Pruitt that brag about deregulation. Employees say it feels like a slap in the face.
Pruitt's actions provide a glimpse into what he means by "environmental stewardship."