Graham said Saturday that Twitter moderators believe the Department of Homeland Security is more of a threat than the ayatollah of Iran.
Facing a tough battle with Democratic contender Jaime Harrison, the South Carolina senator said his number-one priority, if he got elected, was another coronavirus stimulus package.
The pair are due to go head-to-head on Friday evening amid a tight race for the Senate seat currently held by Graham in South Carolina.
The Democratic contender for South Carolina told "Late Show" host Stephen Colbert "Lindsey Graham's word isn't worth much of anything."
Graham has found himself in a surprisingly tight race with Democrat Jaime Harrison.
However, the numbers divided differently when it came to early voters and those who had not yet voted.
"Lindsey Graham, a political parasite with a record of lies and personal betrayals," the ad begins.
"Why should I take the risk of her infecting other people?" asked the 69-year-old poll worker in Chester County.
Harrison, former chair of the South Carolina Democratic Party, has gained national recognition for his fight to unseat Graham, who has served in the U.S. Senate since 2003.
The South Carolina Republican senator has trailed his Democratic challenger in fundraising and faces a tough test to retain his seat.
"We started as a 17-point underdog. Today, I'm honored to accept the endorsement of the oldest newspaper in South Carolina, @thestate. Change is coming, folks," Harrison wrote on Twitter alongside a link to The State's endorsement, written by members of its editorial board.
The South Carolina Republican is still forecast to win, but his better-funded rival is gaining ground in the run up to the vote.
The South Carolina senator again asked conservatives for increased financial support to his reelection campaign during a Fox interview.
As a recent poll showed him leading the incumbent Republican senator by just two points, the Democratic candidate called for a $10 million donations goal.
Graham's Democrat rival raised $57 million in the third quarter, and said this had all been spent on campaigning already.
"Yes, we raised $57 million, but we spent $60 million," Harrison said. "But that is what we had to do in order to get this thing to toss-up status, in order to bridge the gap."
"Help me get my message out," the incumbent Republican from South Carolina said.
The poll, which was conducted by Morning Consult, found 47 percent of South Carolina respondents saying they'd vote for Harrison, while 45 percent sided with Graham.
"[Lindsey Graham] believes that he represents the interest in Washington, D.C. instead of representing the interests of the people in South Carolina," Jaime Harrison said Wednesday.
In the video, the voice of South Carolina Senator Lindsey Graham can be heard instead of Ghostface, the iconic character from the "Scream" series of films.
The Democratic challenger has opened up a one-point lead over the Republican incumbent with just weeks to go until polling day.
Graham's campaign announced he's raised $28 million during the third quarter, while opponent Jamie Harrison raised $57 million.
South Carolina Senator Lindsey Graham later told reporters he made the comment "with dripping sarcasm."
Graham has served as a senator for the traditionally red state since 2003, but several polls have shown Harrison tied in popularity.
Oscar-winning actress Patricia Arquette was among those to share their story.
Despite falling behind in fundraising, Graham re-opened a polling lead over Harrison that he hasn't enjoyed in nearly a year.
Harrison raised $57 million from July through September, the highest quarterly fundraising for a Senate candidate in U.S. history.
Jaime Harrison, the Democrat running against Graham in South Carolina's senate race, announced Sunday his campaign had established new fundraising records.
The senator was asked about race and police brutality during a revamped debate with Jaime Harrison.
Democratic Senate candidate Harrison asked for Graham to be tested for the coronavirus ahead of their second debate.