Authorities said they are still investigating the motives of the 22-year-old suspect.
"Losing your family in a split-second like that is not going to be easy for anybody," a neighbor told WLS news in Chicago.
"Lucky they aren't both dead."
The 18-wheeler crashed through a concrete wall of a San Antonio hotel, which suffered damaged windows as well.
"If I'm suffering in a traffic jam, everyone should too as well," said the driver of a semi who tried to prevent illegal passing.
While the Department of Transportation has promoted the use of speed cameras, several states and cities have had problems with them.
"We have not seen a mass casualty traffic collision like this before," a police spokesperson said this weekend.
The Transportation Department announced a National Roadway Safety Strategy to help curb an increase in traffic deaths since the pandemic started.
"These fatalities are unacceptable, alarming and preventable," said the director of the state's Department of Transportation.
With Christmas less than a week away, the roads could be dangerous as the NHTSA warned alcohol-related deaths are "more prevalent during the holidays."
Video captured the trooper and a motorist barely escaping the violent crash by less than a second.
Anonymous social media accounts resurfaced a long-running hoax after an SUV sped through a Christmas parade in Wisconsin, killing several people.
Law enforcement agencies began reporting major upticks in speeding and impaired driving almost immediately after the pandemic began.
A spokesperson for the NYPD told Newsweek that three "on-duty Traffic Enforcement Agents" reported that they were assaulted by two individuals.
Although there appeared to be no damage to the road, both northbound and southbound lanes of North Carolina Highway 87 were closed down after the crash.
"My son was in a bad accident and didn't make it. My heart is just so broken," said his mother, Tassie, in a posting on his Instagram.
Two dogs were found in the cab of the vehicle after it smashed into the side of the house in Braintree on Saturday.
Diane Everett was killed after losing control of her 2012 Honda CBR motorcycle, while taking part in a memorial ride for her son Michael Jr.
A Wisconsin man was pulled over by police after reports of erratic driving. Officers found empty beer cans in his vehicle and a chicken that had been riding on his shoulder.
The Malanda Millaa Millaa Road was only recently repaired, but it did not hold up well in the sun.
All of those killed were under 10 years of age.
The National Safety Council estimates 38,300 people were killed and 4.4 million injured on U.S. roads in 2015.
Improving economy, lower gas prices among reasons suspected for increase in traffic deaths.