Although there appeared to be no damage to the road, both northbound and southbound lanes of North Carolina Highway 87 were closed down after the crash.
"My son was in a bad accident and didn't make it. My heart is just so broken," said his mother, Tassie, in a posting on his Instagram.
Two dogs were found in the cab of the vehicle after it smashed into the side of the house in Braintree on Saturday.
Diane Everett was killed after losing control of her 2012 Honda CBR motorcycle, while taking part in a memorial ride for her son Michael Jr.
A Wisconsin man was pulled over by police after reports of erratic driving. Officers found empty beer cans in his vehicle and a chicken that had been riding on his shoulder.
The Malanda Millaa Millaa Road was only recently repaired, but it did not hold up well in the sun.
All of those killed were under 10 years of age.
The National Safety Council estimates 38,300 people were killed and 4.4 million injured on U.S. roads in 2015.
Improving economy, lower gas prices among reasons suspected for increase in traffic deaths.