U.S. Open 2019: How to Watch Serena Williams, Roger Federer, Novak Djokovic Second Round Matches, Start times, Live Stream

Roger Federer, Novak Djokovic and the Williams sisters are all in action on Wednesday as the U.S. Open moves into the second round.

The Swiss, a five-time winner at Flushing Meadows, plays Bosnia-Herzegovina's Damir Dzumhur in the afternoon session, while Djokovic takes on Argentina's Juan Ignacio Londero in the evening.

The world No. 1 will be followed on the court by Serena Williams, who plays fellow American Catherine McNally for a spot in the third round.

Serena Williams, who is chasing a record-equaling 24th Grand Slam singles title, looked back to her best in a straight sets demolition of Maria Sharapova on Monday. The No. 8 seed took just 59 minutes to beat the Russian for the 19th consecutive time, winning 6-1, 6-1.

The elder of the Williams sisters, Venus, will be in action earlier in the day when she takes on Elena Svitolina in the second match at the Louis Armstrong Stadium.

The tournament's No. 5 seed, the Ukrainian is a very difficult opponent for Venus Williams, who has reached at least the third round of the U.S. Open in each of her last five appearances.

The women's tournament has already lost Sloane Stephens, who was a surprise casualty in the first round. On Tuesday, the No. 11 seed lost 6-3, 6-4 to 20-year-old Russian Anna Kalinskaya.

"I was playing one good point, one bad point, one good point,'' she said in her press conference. "The inconsistency doesn't help me at all."

There was more positive news for Coco Gauff, as the teenager erased a one-set deficit to beat Russia's Anastasia Potapova 3-6, 6-2, 6-4 in her debut at Flushing Meadows.

"Honestly, I mean, I really don't remember the match too well," the 15-year-old said after the her win. Because everything is still a blur."

In the men's tournament, world No. 2 Rafael Nadal cruised through to the second round after beating Australia's John Millman 6-3, 6-2, 6-2.

Fellow Australian Nick Kyrgios defeated Steve Johnson 6-3, 7-6 (1), 6-4 in a match that didn't begin until 11 p.m. ET and finished at 1 a.m. ET on Wednesday morning.

In a major upset, No. 4 seed Dominic Thiem lost 4-6, 6-3, 3-6, 2-6 against unranked Italian Thomas Fabbiano and No. 8 seed Stefanos Tsitsipas lost 4-6, 7-6 (5), 6 (7)-7 9), 5-7 to Russia's Andrey Rublev.

Here's everything you need to know to keep up with the action on Wednesday.

Second round start time

Actions begins at 11 a.m. ET with six matches on schedule. Play at the Arthur Ashe Stadium doesn't begin until 12 p.m., with Roger Federer scheduled to play in the second match of the afternoon session.

Novak Djokovic opens up the evening session at the Arthur Ashe Stadium at 7 p.m., followed by Serena Williams.

TV channel

The tournament is broadcast exclusively across ESPN channels, with coverage beginning at 11 a.m. and running until 11 p.m. ET on Tuesday on both ESPN and ESPN+.

Live stream

Fans can watch the action online via the WatchESPN app and on ESPN.com.

Serena Williams
Serena Williams of the United States hits a backhand against Maria Sharapova of Russia in the first round of the US Open in Arthur Ashe Stadium at the USTA Billie Jean King National Tennis Center on August 26 in New York City. TPN/Getty

Second round full schedule

French Open champion Ashleigh Barty and 2016 U.S. Open finalist Karolina Pliskova are in action on Wednesday, along with No. 10 seed Madison Keys and No. 16 seed Johanna Konta.

Aside from Roger Federer and Novak Djokovic, No. 7 seed Kei Nishikori, No. 12 seed Borna Coric and No. 15 seed David Goffin are all scheduled to play in the second round.

The full schedule is available here.

Odds

According to Oddschecker, Novak Djokovic remains the runaway favorite to defend his title. The world No. 1 is even odds to win the U.S. Open, while Rafael Nadal is at 11/4 and Roger Federer is a 17/2 shot.

In the women's tournament, Serena Williams is a 7/2 favorite, followed by Simona Halep at 8/1 and Karolina Pliskova at 9/1.

U.S. Open 2019: How to Watch Serena Williams, Roger Federer, Novak Djokovic Second Round Matches, Start times, Live Stream | Sports