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By Gabe Whisnant
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The Trump administration launched TrumpRx on Thursday, a new government-hosted website it says will help Americans access discounted prescription drugs by connecting them directly with pharmaceutical manufacturers.
The rollout comes as health care costs and broader cost-of-living pressures remain major concerns for consumers.
TrumpRx does not sell medications itself. Instead, administration officials say, the site serves as a facilitator, directing users to participating drugmakers’ direct-to-consumer websites where eligible medications can be purchased, typically as cash transactions.
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The site will also offer coupons that can be used at pharmacies and will launch with more than 40 medications, including weight-loss drugs such as Ozempic and Wegovy.
“You’re going to save a fortune,” President Donald Trump said at the site’s unveiling. “And this is also so good for overall health care.”
Trump introduced the platform alongside Centers for Medicare and Medicaid Services Administrator Dr. Mehmet Oz, Health Secretary Robert F. Kennedy Jr., and Joe Gebbia, director of Trump’s National Design Studio.

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What Is TrumpRx?
Trump first previewed TrumpRx in September while announcing the initial round of agreements with pharmaceutical companies aimed at lowering U.S. drug prices to match the lowest prices paid in other developed nations. He later said the website would provide “massive discounts to all consumers,” though administration officials have acknowledged that savings will vary by drug and manufacturer.
TrumpRx is part of a broader administration effort to highlight drug pricing agreements reached with major pharmaceutical companies, including Pfizer, Eli Lilly and Merck. Under those deals, companies agreed to lower prices for certain Medicaid drugs to what the administration calls “most-favored-nation” pricing.
“We're tired of subsidizing the world,” Trump said at the event on the White House campus that lasted roughly 20 minutes.
How Much Could Customers Save on Drugs?
According to a White House fact sheet, participating drugmakers have agreed to sharply reduce list prices on select medications, with examples cited including the cholesterol drug Repatha falling from about $573 to $239 and the diabetes drug Jentadeuto dropping from about $525 to $55 when sold through the platform.
Pfizer announced in October that its prescription drugs would be offered through the site. Trump has also said discounted drugs from Merck will be available.
In December, Trump announced that nine major pharmaceutical companies agreed to join his "most favored nation" pricing policy, bringing down the price of prescription drugs for Medicare and Medicaid recipients. The deal ensured that drugs will be sold at reduced prices, with many sold at the same price that they're sold at overseas, which will be purchased through the TrumpRx platform at "massive discounts," Trump has said.
Administration officials have said prices on TrumpRx could be as much as 80% lower than typical list prices for participating drugs, though savings will vary by medication and manufacturer. Some manufacturers have also agreed to launch select new drugs at discounted prices for consumer markets through TrumpRx.
The White House has emphasized that the discounts apply to cash purchases and that insured patients may still pay less through their health plans, with exact savings unclear until full pricing comparisons are revealed.
The site is part of a broader effort by the Trump administration to highlight its approach to addressing high costs. Affordability has emerged as a political challenge for Trump and his Republican allies ahead of November’s midterm elections, as many Americans remain concerned about the rising cost of housing, groceries, utilities and other everyday expenses.
Will Zepbound Be Discounted Through TrumpRx?
Starting in early 2026, the weight-loss drug Zepbound will be available for approximately $346 per month through the TrumpRx.gov initiative. This program, in collaboration with Eli Lilly, aims to significantly reduce costs from the list price of $1,086. Prices for the injectable medication are expected to further decline to $250 over 24 months.
Under the plan, weight-loss drugs Ozempic and Wegovy would be priced at about $350 a month through TrumpRx, down from current list prices of roughly $1,000 and $1,350, respectively, according to the White House fact sheet.
Administration officials said that if an oral version of Wegovy or similar GLP-1 drugs is approved, initial doses would be priced at about $150 a month through TrumpRx. The administration also said the lower prices would allow Medicare and Medicaid to cover obesity drugs at reduced cost, with Medicare prices for Ozempic, Wegovy, Mounjaro and Zepbound set at about $245 a month.
According to the White House, Medicare beneficiaries would pay a monthly copayment of about $50, and state Medicaid programs would also be eligible to purchase the drugs at the reduced prices.
Updates: 2/5/26, 7:51 p.m. ET: This article was updated with new information and remarks.
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