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By Rowan Fisher-Shotton
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Christian McCaffrey carried the San Francisco 49ers to a 12-5 record and a Wild Card Round win over the Philadelphia Eagles last year.
He finished the season as the team's leading rusher and receiver, racking up 1,202 rushing yards and 10 rushing touchdowns on 311 carries, along with 924 receiving yards and seven receiving touchdowns.
That success came despite several key injuries on both sides of the ball, including Fred Warner, Nick Bosa, George Kittle, Ricky Pearsall, and Brock Purdy. The 49ers will again need to lean on McCaffrey in 2026 if they want to compete in a loaded NFC West division, and a crucial part of keeping him healthy will be the offensive line.
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Unfortunately, on Monday, San Francisco lost one of their newest members, offensive tackle Vederian Lowe, who is now set to miss "extended time" with a high ankle sprain, according to local reporters.
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Lowe signed a two-year, $12 million deal with the 49ers this offseason after spending the last three seasons with the New England Patriots.
After starting 13 games for the Patriots in 2024 at left tackle, Lowe started just four games last season, backing up New England's first-round pick, Will Campbell. Lowe played 318 snaps (29%) and posted a 61.4 overall PFF grade with the Patriots last season, which ranked 63rd of 89 qualified tackles. He allowed 15 total pressures, two hits, and one sack all year.
Lowe wasn't brought in to be a starter, but as the primary backup to 38-year-old Trent Williams — who has dealt with injuries of his own over the years — his would've been the first name called had any issues come up. Any extended absence now shifts the lineup considerably.
High ankle sprains can take anywhere from a couple of weeks to up to three months to fully heal, depending on the severity of it.
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